ID H3GW37_PHYRM Unreviewed; 590 AA.
AC H3GW37;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Glycosyl hydrolase family 30 TIM-barrel domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Phytophthora ramorum (Sudden oak death agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra81642, ECO:0000313|Proteomes:UP000005238};
RN [1] {ECO:0000313|Proteomes:UP000005238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
RN [2] {ECO:0000313|EnsemblProtists:Phyra81642}
RP IDENTIFICATION.
RC STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra81642};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC {ECO:0000256|ARBA:ARBA00005382}.
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DR EMBL; DS566059; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3GW37; -.
DR STRING; 164328.H3GW37; -.
DR EnsemblProtists; Phyra81642; Phyra81642; Phyra81642.
DR VEuPathDB; FungiDB:PSURA_81642; -.
DR eggNOG; KOG2566; Eukaryota.
DR HOGENOM; CLU_014379_1_2_1; -.
DR InParanoid; H3GW37; -.
DR OMA; PIMGDWF; -.
DR Proteomes; UP000005238; Unassembled WGS sequence.
DR GO; GO:0004348; F:glucosylceramidase activity; IBA:GO_Central.
DR GO; GO:0006680; P:glucosylceramide catabolic process; IBA:GO_Central.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR033452; GH30_C.
DR InterPro; IPR001139; Glyco_hydro_30.
DR InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR Pfam; PF02055; Glyco_hydro_30; 1.
DR Pfam; PF17189; Glyco_hydro_30C; 1.
DR PRINTS; PR00843; GLHYDRLASE30.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000005238};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..590
FT /note="Glycosyl hydrolase family 30 TIM-barrel domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003586971"
FT DOMAIN 104..470
FT /note="Glycosyl hydrolase family 30 TIM-barrel"
FT /evidence="ECO:0000259|Pfam:PF02055"
FT DOMAIN 476..541
FT /note="Glycosyl hydrolase family 30 beta sandwich"
FT /evidence="ECO:0000259|Pfam:PF17189"
SQ SEQUENCE 590 AA; 64226 MW; 660E7C6A837335D5 CRC64;
MRVLPPARLL PAAVALLAGR CGVTASCSSW STRFQQDIEG VCTCNATSCD SVSTEYLSLS
SSQVGVFQTS KAGDRLVYST LGIDAGSDDA ADLIIDSTTT YQEIIGFGGA FTDAAAINVY
LMDTDVQQLI LDAYFSDTGL QYSLGRIPIA STDFSEYVYS YSPSVDDFEM ANFSIDADKE
PLSNKLSLIQ RALSETSAAS RNLTLFASSW APPVWMTTSN TTLNCEMNGY PGGEYWEALA
LYYSKFIGAY EAEGVPIWGL TTQNEPTKQE LATKFWQSLR FNTTTERDFI KRDLGPLMKE
KHPDVKIIIL DDQKDLLLDW NASLLDEEAR GYVSGVGVHW YKNLDFAFGT SGDFDDLVTF
HAEYPDIFIL ATEACEGSLV KGLGTGMGPH LFDYNNITWQ RGENYARDII NDLASFASGW
TDWNLVLNTT GGPNWADNQV DAPILVDEEG GAEFYKQPIY YVMGHFSKFL VPGSLQVEMN
VSSNASSTLE NVDRVAFVTP EGQVVVVLSN RDSTEKSIRI KLMVEVRAVT VVLPANTVQT
VLFPAFGLAI GSEGSEGSPS ASSSATSTSP TTMNLVVALI LSGFVASRQA
//
