ID   H3JZ48_HELPX            Unreviewed;       832 AA.
AC   H3JZ48;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=DupA {ECO:0000313|EMBL:BAL46841.1};
GN   Name=dupA {ECO:0000313|EMBL:BAL46841.1};
OS   Helicobacter pylori (Campylobacter pylori).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=210 {ECO:0000313|EMBL:BAL46841.1};
RN   [1] {ECO:0000313|EMBL:BAL46841.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Okinawa338 {ECO:0000313|EMBL:BAL46841.1};
RA   Takahashi A., Shiota S., Matsunari O., Watada M., Suzuki R., Nakachi S.,
RA   Kinjo N., Kinjo F., Yamaoka Y.;
RT   "Long type intact dupA without mutation as a marker for gastroduodenal
RT   diseases in Japan.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:BAM75287.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Okinawa337 {ECO:0000313|EMBL:BAM75336.1}, and Okinawa338
RC   {ECO:0000313|EMBL:BAM75287.1};
RA   Takahashi A., Shiota S., Matsunari O., Watada M., Suzuki R., Nakachi S.,
RA   Kinjo N., Kinjo F., Yamaoka Y.;
RT   "Intact long-type dupA as a marker for gastroduodenal diseases in Okinawan
RT   subpopulation, Japan.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TrbE/VirB4 family.
CC       {ECO:0000256|ARBA:ARBA00006512}.
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DR   EMBL; AB649949; BAL46841.1; -; Genomic_DNA.
DR   EMBL; AB739531; BAM75287.1; -; Genomic_DNA.
DR   EMBL; AB739586; BAM75336.1; -; Genomic_DNA.
DR   AlphaFoldDB; H3JZ48; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR018145; CagE_TrbE_VirB_cntrl_dom.
DR   InterPro; IPR002543; FtsK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR019476; T4SS_TraD_DNA-bd.
DR   PANTHER; PTHR30121:SF10; BLR3062 PROTEIN; 1.
DR   PANTHER; PTHR30121; UNCHARACTERIZED PROTEIN YJGR-RELATED; 1.
DR   Pfam; PF03135; CagE_TrbE_VirB; 1.
DR   Pfam; PF01580; FtsK_SpoIIIE; 1.
DR   Pfam; PF10412; TrwB_AAD_bind; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          210..406
FT                   /note="CagE TrbE VirB component of type IV transporter
FT                   system central"
FT                   /evidence="ECO:0000259|Pfam:PF03135"
FT   DOMAIN          429..500
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|Pfam:PF01580"
FT   DOMAIN          655..755
FT                   /note="Type IV secretion system coupling protein TraD DNA-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF10412"
SQ   SEQUENCE   832 AA;  96370 MW;  9E840F7493BDADD9 CRC64;
     MFLGLEGFKK FIFNFLSSCI PRQYSLVQEN NINGKFDEKF VLTHKGNLVG AISLSGITYS
     NFDKEEVATQ FLYRTQALNE LIDGVTLRIV AKRRNIKTQT IYNKDGVSKY AKKIVNAYEK
     NKEFYITTYY LIIETKSVNI KGLLEKWKAK MTTDKYVNNN EEKPLKDNLK NSEAQKQEVY
     KIKKNAVENK ELQDKATLLA EILNKMSSIL TDFEPKSLSS DDLLNLYAEY CNGHYCDFKY
     KQGRLSDGNI QSHLYFKKDH FIHDYNGIET FKRFIAVKAY DVDNITSLAL SNLLCEKFNL
     DILLTIEAMD KERALFFIRE RKKRSKDISY QNIEYLEQMV STDRAQIQKV SLSIMVFANS
     KKELDKKSII VYNTLKKERF SAVLESINMR PIFFSFFPER NFLNSRLRPQ TSQNIASLIM
     FEKYQEGFKE NSWGDCPISV FKNQNGSAHF FNFQAKQGRD RNDNIVGHTM IIGSTGSGKS
     TFISFLIANL LTKYDMSVVA LDRMNGLEIM TDFFEGQYNT ANTDGGFYIN PFSLKDTEEN
     RQFLANWIKF MLNIDSNNQQ DNKASQSIDK VIRDTYNYMG EQKNQINLLE IAKNLGSSEQ
     DFNEILKSQG EKVYFKNFQD CLDFSKSPLS VINMDVFAND KKLMGLIAMY LFHKLFFEAK
     EHNKPFFLFI DETKDYIMHP IMFTYIANAL AQARKINGTL CMAFQKISQV KELGIDKAKS
     LIGNLSQVII YPTKDTDELI ECGVPLSDSE INFLHNTDMR ARQVLVKNIV TNASAFIEID
     LKKDLQELLY ILDSNAGNRK ILNDLKKINQ ETYKEEYLKI KMKKESENVQ HV
//