ID H3NRZ3_9GAMM Unreviewed; 856 AA.
AC H3NRZ3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Glycine cleavage system T protein (Aminomethyltransferase) {ECO:0000313|EMBL:EHQ58004.1};
GN ORFNames=OMB55_00017480 {ECO:0000313|EMBL:EHQ58004.1};
OS gamma proteobacterium HIMB55.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX NCBI_TaxID=745014 {ECO:0000313|EMBL:EHQ58004.1, ECO:0000313|Proteomes:UP000003408};
RN [1] {ECO:0000313|EMBL:EHQ58004.1, ECO:0000313|Proteomes:UP000003408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HIMB55 {ECO:0000313|EMBL:EHQ58004.1,
RC ECO:0000313|Proteomes:UP000003408};
RX PubMed=22493201; DOI=10.1128/JB.00171-12;
RA Huggett M.J., Rappe M.S.;
RT "Genome Sequence of Strain HIMB55, a Novel Marine Gammaproteobacterium of
RT the OM60/NOR5 Clade.";
RL J. Bacteriol. 194:2393-2394(2012).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHQ58004.1}.
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DR EMBL; AGIF02000001; EHQ58004.1; -; Genomic_DNA.
DR AlphaFoldDB; H3NRZ3; -.
DR STRING; 745014.OMB55_00017480; -.
DR PATRIC; fig|745014.4.peg.1767; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000003408; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:EHQ58004.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003408};
KW Transferase {ECO:0000313|EMBL:EHQ58004.1}.
FT DOMAIN 9..382
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 385..441
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 444..725
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 792..840
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 856 AA; 95030 MW; EC59511F3D51F42E CRC64;
MADLPKHARV VVIGQGGIVG ASVVHHLIEE GWDDIVGLEK SAIPTDIGST SHASDFCYMT
SHDKLTVWTS QYSREFYKKR GNYIEIGGLE VARKDDDDRM LELIRKVGSG KAFGTKAYMI
SAAEAKEKFP LLEEDQIQGA MWDPEAGLVT PRSQKVAGDL VDEAVASGKL TTFAYTPATK
VLVEDGVAVG VETPKGTIMA DHIVLCAGIW GSLISETANV KLPLMPLEHP LLFFGPWDHL
EGTGKDIVYP LLRDQGNSAY VRDTGDPTTP EGGLLEWGYY EPSEPRLVEA RDIAEPGEAR
LSPSMRDMTL DQVMDAFERA IELTPILGEL GWEERRSFNG LLSVTVDSGS IIGESVEARN
LWLCEAVWVK DGPGAGKLLA EWMTHGRTSM DPHSIDPARH YPIQKTDEYI RGHCYESSQK
VYTPAVHPRE PFATSRGMRV SPFYEREVAL GGYFMEVAGW ERAHGYAANE ATLLAKYRDQ
VPVREAEWDN RHFWEVSNAE QLAMSDGVGM INLSHFAIFD VEGSDAEALM EYLSVAKVGG
DTATGKGVYT HFLDQAGGIR SDLTIIRLAE DCFRVVCGGD TGNRDYVWMR DMSERKGFPN
VTFHDRSEEL STLGLWGPEA RVTLAKLMDD PESISNESFP FATTKEITVC GVKVWAFRIS
YVGEQGWELY FPFSDGLAIW DALFELGVTP VGIETYANSR RLEKSLRLQN ADLETDYNLY
EAALARPKVK AADFHGKEAY VQQRELDEQA AYLCTFVLKD TTDSNGVVRY PIGNWPILDR
ESKEVLIDSH GRRSYTTSMS FGPSLGLNIA MGYLPADKAK EGNIVLIEYF GEHYEAEVMK
VGYGALLDPT NERPKS
//
