ID H3ZQQ5_THELN Unreviewed; 298 AA.
AC H3ZQQ5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Phosphomethylpyrimidine kinase {ECO:0000313|EMBL:EHR77631.1};
GN ORFNames=OCC_09391 {ECO:0000313|EMBL:EHR77631.1};
OS Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=523849 {ECO:0000313|EMBL:EHR77631.1, ECO:0000313|Proteomes:UP000015502};
RN [1] {ECO:0000313|EMBL:EHR77631.1, ECO:0000313|Proteomes:UP000015502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51850 / DSM 5473 / JCM 8560 / NS-C
RC {ECO:0000313|Proteomes:UP000015502};
RX PubMed=22493191; DOI=10.1128/JB.00123-12;
RA Gardner A.F., Kumar S., Perler F.B.;
RT "Genome sequence of the model hyperthermophilic archaeon Thermococcus
RT litoralis NS-C.";
RL J. Bacteriol. 194:2375-2376(2012).
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DR EMBL; CP006670; EHR77631.1; -; Genomic_DNA.
DR RefSeq; WP_004069742.1; NC_022084.1.
DR AlphaFoldDB; H3ZQQ5; -.
DR STRING; 523849.OCC_09391; -.
DR PaxDb; 523849-OCC_09391; -.
DR GeneID; 16549127; -.
DR KEGG; tlt:OCC_09391; -.
DR HOGENOM; CLU_054903_0_0_2; -.
DR OrthoDB; 26806at2157; -.
DR Proteomes; UP000015502; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR019293; ThiN.
DR PANTHER; PTHR40730; TRANSCRIPTIONAL REGULATOR PROTEIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR40730:SF5; TRANSCRIPTIONAL REGULATOR PROTEIN-LIKE PROTEIN; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF10120; ThiP_synth; 1.
DR SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EHR77631.1};
KW Transferase {ECO:0000313|EMBL:EHR77631.1}.
FT DOMAIN 26..54
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 298 AA; 33649 MW; 964387227926F95F CRC64;
MKTPCEFWAE EVMPNLRANV ARILYSKGLT QAKIAEHLGI TQAMVSKYLT GKYRRLNGEL
GKEVEKVAQE VVGLILYGAK KEDLVRFLNR KFFEMFRSGI LCRGYLDYIG SSDESLCREI
FTEEPSRTQI LEELSLALSE LLRDEKFLEL IPEVRSNFAY SLPKPKEKND VAAIPGRITV
VKGKAYALPP EFGVSEHMAE VLIGLSEIFP EVRSVLNIRY DKKISGALKK AGFKVGTVEK
SERSEEETVK LITVEFKKKG ILDAVIDKGG FGIEPCVYIF GKSPIEVVEK VKKLERFL
//
