ID H5SAT5_9BACT Unreviewed; 859 AA.
AC H5SAT5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Hypothetical conserved protein {ECO:0000313|EMBL:BAL53271.1};
GN ORFNames=HGMM_F06C06C16 {ECO:0000313|EMBL:BAL53271.1};
OS uncultured Planctomycetota bacterium.
OC Bacteria; Planctomycetota; environmental samples.
OX NCBI_TaxID=120965 {ECO:0000313|EMBL:BAL53271.1};
RN [1] {ECO:0000313|EMBL:BAL53271.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16309394; DOI=10.1111/j.1462-2920.2005.00881.x;
RA Nunoura T., Hirayama H., Takami H., Oida H., Nishi S., Shimamura S.,
RA Suzuki Y., Inagaki F., Takai K., Nealson K.H., Horikoshi K.;
RT "Genetic and functional properties of uncultivated thermophilic
RT crenarchaeotes from a subsurface gold mine as revealed by analysis of
RT genome fragments.";
RL Environ. Microbiol. 7:1967-1984(2005).
RN [2] {ECO:0000313|EMBL:BAL53271.1}
RP NUCLEOTIDE SEQUENCE.
RA Takami H., Noguchi H., Takaki Y., Uchiyama I., Toyoda A., Nishi S.,
RA Chee G.-J., Arai W., Nunoura T., Itoh T., Hattori M., Takai K.;
RT "A Deeply Branching Thermophilic Bacterium with an Ancient Acetyl-CoA
RT Pathway Dominates a Subsurface Ecosystem.";
RL PLoS ONE 7:e30559-e30559(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP011653; BAL53271.1; -; Genomic_DNA.
DR AlphaFoldDB; H5SAT5; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..635
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 642..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..736
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 742..774
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 251..382
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 832..859
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 859 AA; 95206 MW; 8A795047BA4E98E3 CRC64;
MKEDQGSVSH TPAPRHGDFF SRYNLAILCC VCFLIPFMWV GADRALLSNK NDVKSWLPDT
YQETTTFEWY RKHFESDMFI LASWEGCTLD SPKLELLSRR LALELQRPED DPYRFFKKVI
TGKQVVDQLV ASQGLTREQA IERLRGFLVG QDGQQTCLVL IIDPKAEERW ENHFHGNPRK
KFLHAVVESV YAAAKEICDI KPEQLHLGGP PVDNVAIDVE GQRSLVRLAI VCGAVGAVMA
WWCLRSWVLT LVVFSTGVYS AGLSMILVWL TGTDMNAILL TMPALVYVAA VSGAIHLANY
YRDTVRTHMS WGLPDPTVGA PGKALRSAFL PLFLATSTTA FGLASLTVSE LVPIQTFGIY
SAAGIIVSFL FLCLYVPSML QEWPIPEIAR SRQAFKFDPG RWAGWRKVGD FIIARPSWVV
AGCIVLMLIG AMGASRIQTS VKLMRLFSPE ATIIRDYAWL EEKLGPLVPM EVVIKVDRDK
AKLDVLEQMK LVSEVQRAIK QLPDVGSVIA APTFARPLPS QAGLIEKRTW IVQLRRHRED
LRDYWSEEGN TELWRVSARV KALTDLDYGN FVEDIRRQVE PVLAKYRSQG VDGISAVYTG
LVPLVYKAQH SLLNGLLTGF AGDLVIIAIA LMFVMRDWSA GLLLGFASVF PIAIVFGFMG
LLGIVVDVGT VMTPAVALGV TVDDAIHFML WCRHGQERGL SRADSIRFAY GDCAQAIYQS
WGVIGLGLSA FALSSFTPTQ RFGYLMFAML TASSFGNLVL LPALLASPLA NFFWKSGERI
AARKRGRGEG HHAPDLHPHL VADRREEPAE ELVGVGAGSE TLEFLGLSAQ RGAGAGKVSQ
RHGSAPRRPD RNRLPRHPR
//
