ID   H5WIZ3_9BURK            Unreviewed;       516 AA.
AC   H5WIZ3;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II {ECO:0000313|EMBL:EHR73634.1};
GN   ORFNames=BurJ1DRAFT_4849 {ECO:0000313|EMBL:EHR73634.1};
OS   Burkholderiales bacterium JOSHI_001.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX   NCBI_TaxID=864051 {ECO:0000313|EMBL:EHR73634.1, ECO:0000313|Proteomes:UP000004674};
RN   [1] {ECO:0000313|EMBL:EHR73634.1, ECO:0000313|Proteomes:UP000004674}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JOSHI_001 {ECO:0000313|EMBL:EHR73634.1,
RC   ECO:0000313|Proteomes:UP000004674};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Zeytun A., Lu M., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Smith J., Lewis G.,
RA   Woyke T.;
RT   "Noncontiguous Finished sequence of Burkholderiales bacterium JOSHI_001.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM001438; EHR73634.1; -; Genomic_DNA.
DR   AlphaFoldDB; H5WIZ3; -.
DR   STRING; 864051.BurJ1DRAFT_4849; -.
DR   eggNOG; COG0318; Bacteria.
DR   HOGENOM; CLU_000022_59_0_4; -.
DR   OrthoDB; 9766486at2; -.
DR   BioCyc; BBAC864051:G1H30-4828-MONOMER; -.
DR   Proteomes; UP000004674; Chromosome.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   CDD; cd05941; MCS; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR43201:SF8; FATTY ACID COA SYNTHETASE FAMILY; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:EHR73634.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004674}.
FT   DOMAIN          39..375
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          426..501
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   516 AA;  55601 MW;  A7449A7ABBE58C55 CRC64;
     MGNQNLFAAL RAGFAGQLDA TVIETADGPS GEKAAPLYYT ARDLERGTAM LANLLASLKL
     PDGARVAVQT EKSVEALMLY LAVLRAGYVY LPLNTAYQAS EIEYFIGNAQ PAVVVCSPKN
     FAWVSRIAFS AGTKSVFTLG DDRTGSLLER AAHHSDQHVP AIKRSDDLAA ILYTSGTTGR
     SKGAMLTHGN LLSNAQVLNR YWDWRSTDVL VHALPIFHVH GLFVASHGAL LAGAKMVWFN
     RFDPAATVAR LPQATVFMGV PTLYVRMLGE AALTPAQCAH MRLFISGSAP LLLETFQAWQ
     QRSGHTILER YGMSETAMLT SNPCRPADGD RRGGTVGPAL PGVMLRVRND DGSDAGVDEI
     GGIQVKGPNV FKGYWQMPEK TKEEFTDDGW FKTGDVGRRS ADGYVTIVGR SKDLIISGGY
     NVYPAEIEGV INDMTGVAES AVIGVPHADF GEAVVAVLVP RPGAALDAAA ITAELKSRIA
     NFKVPKRVFV VKELPRNTMG KVQKNLLREQ HQGLFA
//