ID H5WJW3_9BURK Unreviewed; 362 AA.
AC H5WJW3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|Pfam:PF13676};
GN ORFNames=BurJ1DRAFT_1811 {ECO:0000313|EMBL:EHR70671.1};
OS Burkholderiales bacterium JOSHI_001.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=864051 {ECO:0000313|EMBL:EHR70671.1, ECO:0000313|Proteomes:UP000004674};
RN [1] {ECO:0000313|EMBL:EHR70671.1, ECO:0000313|Proteomes:UP000004674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JOSHI_001 {ECO:0000313|EMBL:EHR70671.1,
RC ECO:0000313|Proteomes:UP000004674};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Zeytun A., Lu M., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Smith J., Lewis G.,
RA Woyke T.;
RT "Noncontiguous Finished sequence of Burkholderiales bacterium JOSHI_001.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM001438; EHR70671.1; -; Genomic_DNA.
DR AlphaFoldDB; H5WJW3; -.
DR STRING; 864051.BurJ1DRAFT_1811; -.
DR eggNOG; COG2815; Bacteria.
DR HOGENOM; CLU_764353_0_0_4; -.
DR Proteomes; UP000004674; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR Pfam; PF13676; TIR_2; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004674};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 244..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 79..181
FT /note="TIR"
FT /evidence="ECO:0000259|Pfam:PF13676"
FT REGION 194..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 37383 MW; 64EED3555AFF7109 CRC64;
MSAEVVPERW IPLAQSSGRK ILSAPSKPGA WHPSVQVPAL RVSLFAGGQI QDGQHAGSPA
VIALVAVTNP GMVEAARPVF ISYARLDQPL VARAVEFLRA GGLNVFVDSQ SIGYGTDWRQ
ALGDAIENAE RVMLFWTAAA AASRWVTREW QWALMRGKKV VPTLLDDTPL PPALARLHAV
TTLRGLFPAP LRRPEDLTAE PFAPDDESQG EDLDPGPADS GWATSNPSTP ASASSGPRAM
PGRLTMIVAS LVVVGVVGGM ALLRPASVPA GSSPVPAAVG TPASAAASAG QGPASSAAPP
ASAAASAATA ASEPALMDVE PDTFLRGPLF ALVMLAGAAL LLLRRLTQNG RARAIVNEVY
SV
//
