ID H5WUM1_9BURK Unreviewed; 315 AA.
AC H5WUM1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:EHR69447.1};
GN ORFNames=BurJ1DRAFT_0565 {ECO:0000313|EMBL:EHR69447.1};
OS Burkholderiales bacterium JOSHI_001.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=864051 {ECO:0000313|EMBL:EHR69447.1, ECO:0000313|Proteomes:UP000004674};
RN [1] {ECO:0000313|EMBL:EHR69447.1, ECO:0000313|Proteomes:UP000004674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JOSHI_001 {ECO:0000313|EMBL:EHR69447.1,
RC ECO:0000313|Proteomes:UP000004674};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Zeytun A., Lu M., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Smith J., Lewis G.,
RA Woyke T.;
RT "Noncontiguous Finished sequence of Burkholderiales bacterium JOSHI_001.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CM001438; EHR69447.1; -; Genomic_DNA.
DR AlphaFoldDB; H5WUM1; -.
DR STRING; 864051.BurJ1DRAFT_0565; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_2_0_4; -.
DR OrthoDB; 9072091at2; -.
DR BioCyc; BBAC864051:G1H30-556-MONOMER; -.
DR Proteomes; UP000004674; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30579; TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30579:SF3; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004674};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 231..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..67
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 315 AA; 34260 MW; CC08F4E3B599A396 CRC64;
MPLPFDPSRI DWNLLRAFVA VLEQGSLTRA AERLDSSQPT LSRQIAALEA QAGAPLFERA
ARRLVPTALG QALAEPAARM LAAAQAMAQA AEGAARGLRG SVRITASEVV STHVLPPLLQ
QLAGAHPEIQ VELVASDRVD NLLQREADIA VRMLRPTQGG VLTRHLADWP LGFFVHRDAL
AAAGGPPTRA TLQRLRWLGF DQSSQLIDGF RAAGMNVDRD FFSFRCDHQP ALFGALCAGL
GVGVALVPLA RRQAQLVQVL TDERLPQLPV WLTARQELRA NRRLRTVFDV LADGLLRWGA
PPALPARPSR RTARH
//
