ID H5X769_9PSEU Unreviewed; 633 AA.
AC H5X769;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Type VII secretion-associated protein, Rv3446c family, C-terminal domain {ECO:0000313|EMBL:EHR49029.1};
GN ORFNames=SacmaDRAFT_0733 {ECO:0000313|EMBL:EHR49029.1};
OS Saccharomonospora marina XMU15.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharomonospora.
OX NCBI_TaxID=882083 {ECO:0000313|EMBL:EHR49029.1, ECO:0000313|Proteomes:UP000004926};
RN [1] {ECO:0000313|EMBL:EHR49029.1, ECO:0000313|Proteomes:UP000004926}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XMU15 {ECO:0000313|EMBL:EHR49029.1,
RC ECO:0000313|Proteomes:UP000004926};
RX PubMed=22768369; DOI=10.4056/sigs.2655905;
RA Klenk H.P., Lu M., Lucas S., Lapidus A., Copeland A., Pitluck S.,
RA Goodwin L.A., Han C., Tapia R., Brambilla E.M., Potter G., Land M.,
RA Ivanova N., Rohde M., Goker M., Detter J.C., Li W.J., Kyrpides N.C.,
RA Woyke T.;
RT "Genome sequence of the ocean sediment bacterium Saccharomonospora marina
RT type strain (XMU15(T)).";
RL Stand. Genomic Sci. 6:265-275(2012).
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR EMBL; CM001439; EHR49029.1; -; Genomic_DNA.
DR RefSeq; WP_009152415.1; NZ_CM001439.1.
DR AlphaFoldDB; H5X769; -.
DR STRING; 882083.SacmaDRAFT_0733; -.
DR eggNOG; COG0443; Bacteria.
DR HOGENOM; CLU_411554_0_0_11; -.
DR OrthoDB; 3333926at2; -.
DR Proteomes; UP000004926; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR CDD; cd10170; HSP70_NBD; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR013126; Hsp_70_fam.
DR InterPro; IPR023840; T7SS_Rv3446c.
DR NCBIfam; TIGR03931; T7SS_Rv3446c; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR PANTHER; PTHR19375:SF184; STRESS-70 PROTEIN, MITOCHONDRIAL; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322};
KW Reference proteome {ECO:0000313|Proteomes:UP000004926};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 457..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 376..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..447
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 633 AA; 68514 MW; EA42473D408744AD CRC64;
MTLRVAVDFG TSSTCVVASV NGREPQVVVV DGQPLLPSAV YAAQDGTLFV GQEAERQAAV
DPSRFEPTPK RRIDEGELLL GDTVLSVVDV VHAVLRRAVS EARRLAGGAE VALLVLTHPA
EWGAVRTRLL RQAAAQLARE VALVPEPVAA AVFHAATFAP TDVNQDRTVE FSGKPGDVLA
VLDLGGGTID VSVVRRVSGN RTGAFEVLAT RGDPSFGGAD IDQVLLEHVG SLVSDADPDA
WEQLVTGREL TDRRRRRVLR QDVRGAKETL SRHAYTDVPM PPPFADAHVT REDLERLIAT
RLGRAVELTS ETIEAAGLRP KQLTAIFLVG GSSRIPMVSR LVHEHTGVVP TTLDQPETVV
ARGALRAVQV IPDRTGMLPG MASQGRFSGP MRAQDRRTDV VARPGYPARQ GRPPTTGPLP
RHPPRGRPMV PPSPPQLHPP AVPLGPARKP PSRRRRVLLW GIAVAAVVAV AAITTVVLVS
RGDDRAAAEG RTFAQYSYKF VAPADWTQTG DNVADRQVVV KPREAQTSED DDLVVVQEFV
LSYDGGSNRA QLARELRDQA DDRPDVYSDF AEHHAFAGRD VIYYTENKPA ATVNWYVLAH
GTAQVSVGCQ EAEMPRRVQQ ACEQIVRTLE FTN
//
