ID H5XHX7_9PSEU Unreviewed; 317 AA.
AC H5XHX7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=deoxyribose-phosphate aldolase {ECO:0000256|ARBA:ARBA00012515};
DE EC=4.1.2.4 {ECO:0000256|ARBA:ARBA00012515};
DE AltName: Full=2-deoxy-D-ribose 5-phosphate aldolase {ECO:0000256|ARBA:ARBA00032755};
DE AltName: Full=Phosphodeoxyriboaldolase {ECO:0000256|ARBA:ARBA00031814};
GN ORFNames=SaccyDRAFT_0655 {ECO:0000313|EMBL:EHR59583.1};
OS Saccharomonospora cyanea NA-134.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharomonospora.
OX NCBI_TaxID=882082 {ECO:0000313|EMBL:EHR59583.1};
RN [1] {ECO:0000313|EMBL:EHR59583.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA-134 {ECO:0000313|EMBL:EHR59583.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Lu M., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Brambilla E.-M.,
RA Klenk H.-P., Woyke T.;
RT "The Noncontiguous Finished sequence of Saccharomonospora cyanea NA-134.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde
CC 3-phosphate; Xref=Rhea:RHEA:12821, ChEBI:CHEBI:15343,
CC ChEBI:CHEBI:59776, ChEBI:CHEBI:62877; EC=4.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000764};
CC -!- PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate
CC degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-
CC deoxy-alpha-D-ribose 1-phosphate: step 2/2.
CC {ECO:0000256|ARBA:ARBA00004816}.
CC -!- SIMILARITY: Belongs to the DeoC/FbaB aldolase family. DeoC type 2
CC subfamily. {ECO:0000256|ARBA:ARBA00009473}.
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DR EMBL; CM001440; EHR59583.1; -; Genomic_DNA.
DR RefSeq; WP_005453551.1; NZ_CM001440.1.
DR AlphaFoldDB; H5XHX7; -.
DR STRING; 882082.SaccyDRAFT_0655; -.
DR eggNOG; COG0274; Bacteria.
DR HOGENOM; CLU_053595_3_0_11; -.
DR OrthoDB; 6579831at2; -.
DR Proteomes; UP000002791; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004139; F:deoxyribose-phosphate aldolase activity; IEA:UniProtKB-EC.
DR GO; GO:0009264; P:deoxyribonucleotide catabolic process; IEA:InterPro.
DR CDD; cd00959; DeoC; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR011343; DeoC.
DR InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR NCBIfam; TIGR00126; deoC; 1.
DR PANTHER; PTHR10889; DEOXYRIBOSE-PHOSPHATE ALDOLASE; 1.
DR PANTHER; PTHR10889:SF3; DEOXYRIBOSE-PHOSPHATE ALDOLASE; 1.
DR Pfam; PF01791; DeoC; 1.
DR SMART; SM01133; DeoC; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
SQ SEQUENCE 317 AA; 33623 MW; AC1EC22CA409DBE8 CRC64;
MATATLPAEL NDAVRDDRSL RRFLHGLPGV DQVGVEQRAA SLATRSIKKN SKLWAIDTAI
SMVDLTTLEG ADTPGKVRSL AAKARRPDPE HPDTPHVAAV CVYPDLAATA VEALAGADIA
VASVATAFPS GRSSRDVKLA DVALAVSAGA TEVDMVIDRG AFLAGRYGQV FEEIQAVKQA
CGDAHLKVIL ETGELATYDN VRRASWLALL AGGDFIKTST GKVSPAATLP VTHVMLQAVR
DWHTATGELR GVKPAGGIRT TKDAVRYLVA VHEVAGPEWL TPSLFRFGAS SLLNDLLLQR
RTQLSGHYSG PDYLALD
//
