ID H5XJP3_9PSEU Unreviewed; 153 AA.
AC H5XJP3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000256|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN ORFNames=SaccyDRAFT_1915 {ECO:0000313|EMBL:EHR60809.1};
OS Saccharomonospora cyanea NA-134.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharomonospora.
OX NCBI_TaxID=882082 {ECO:0000313|EMBL:EHR60809.1};
RN [1] {ECO:0000313|EMBL:EHR60809.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA-134 {ECO:0000313|EMBL:EHR60809.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Lu M., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Brambilla E.-M.,
RA Klenk H.-P., Woyke T.;
RT "The Noncontiguous Finished sequence of Saccharomonospora cyanea NA-134.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000256|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000256|ARBA:ARBA00005952,
CC ECO:0000256|HAMAP-Rule:MF_00073}.
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DR EMBL; CM001440; EHR60809.1; -; Genomic_DNA.
DR RefSeq; WP_005455652.1; NZ_CM001440.1.
DR AlphaFoldDB; H5XJP3; -.
DR STRING; 882082.SaccyDRAFT_1915; -.
DR eggNOG; COG0781; Bacteria.
DR HOGENOM; CLU_087843_2_3_11; -.
DR OrthoDB; 3528057at2; -.
DR Proteomes; UP000002791; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; NusB-like; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR NCBIfam; TIGR01951; nusB; 1.
DR PANTHER; PTHR11078:SF3; ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11078; N UTILIZATION SUBSTANCE PROTEIN B-RELATED; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; NusB-like; 1.
PE 3: Inferred from homology;
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00073};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00073};
KW Transcription antitermination {ECO:0000256|ARBA:ARBA00022814,
KW ECO:0000256|HAMAP-Rule:MF_00073};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00073}.
FT DOMAIN 20..142
FT /note="NusB/RsmB/TIM44"
FT /evidence="ECO:0000259|Pfam:PF01029"
SQ SEQUENCE 153 AA; 16786 MW; F31B07EB664A5A08 CRC64;
MNDESRSSRP ARRGGISRRA SRRRAVELLY EAALRDTDPV TLLSERVGSV DADPVSDYTI
ALVEGVGENR ERIDEVLAEH AQGWSLQRMP PVDLAVLRVG LYELLWAVDV PDPVAIDEAV
GIAKQLSTDD SPRFVNGVLG RIGTIADRLR AVL
//
