ID   H5XMA5_9PSEU            Unreviewed;       923 AA.
AC   H5XMA5;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:EHR63656.1};
GN   ORFNames=SaccyDRAFT_4854 {ECO:0000313|EMBL:EHR63656.1};
OS   Saccharomonospora cyanea NA-134.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharomonospora.
OX   NCBI_TaxID=882082 {ECO:0000313|EMBL:EHR63656.1};
RN   [1] {ECO:0000313|EMBL:EHR63656.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA-134 {ECO:0000313|EMBL:EHR63656.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ovchinnikova G., Lu M., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Pagani I., Brambilla E.-M.,
RA   Klenk H.-P., Woyke T.;
RT   "The Noncontiguous Finished sequence of Saccharomonospora cyanea NA-134.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM001440; EHR63656.1; -; Genomic_DNA.
DR   AlphaFoldDB; H5XMA5; -.
DR   STRING; 882082.SaccyDRAFT_4854; -.
DR   eggNOG; COG5001; Bacteria.
DR   eggNOG; COG5002; Bacteria.
DR   HOGENOM; CLU_000445_70_20_11; -.
DR   Proteomes; UP000002791; Chromosome.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 3.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 4.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 3.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 4.
DR   SMART; SM00091; PAS; 3.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
FT   DOMAIN          263..321
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          368..412
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          443..498
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          529..663
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          672..923
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   923 AA;  100528 MW;  C80D0FB4D259061C CRC64;
     MDLIMEAYTQ DEVSTGRNRE DVVELALAAS AAGTWSVEFP GYGVTWSAEL PEVLGADHDS
     AEAVRERLLE LIEPLTMAAE NCPVWHNFDL EQSHTTPGGE TRWTRFLARA QGNAVTGRVD
     RLVGIATDVT ERRGNTQALA DLADRYRLLV EFSPDGICVH QDGDLVYVNP AAARFVAAEE
     PAALLGRPII DFVSPSAVSE LLRRVSSLGS PGEATKPTKV RLSRLDGGSM LIESVSVRTT
     WKGKPAYQVI MRDISAQKAA EAALRYQAAL VSHVSDAIIG TTSDGMVTSW NPAAERIYGH
     GENAALGRPV GELVGATLDP QAVIAGGGVV EAEHRKADGS ALTVRVSASP MDRGYVLVCA
     DETARRAAER RYRTVVAALD EGVVVTDAHG FVASANPASG RILGLPVEAM IGCSPTLFPL
     YDESGARIPP SEYPSATTRT TGLAMNGRVV RARRPDGRWV WLSMSCRPLD PNATPPYQVV
     TSFTDITERK AIGERLEHDA THDPLTNLAN RTLVLQRLEE ALRRRDGRSP ACVLFIDLDK
     FKVINDSLGH GIGDKVLRIA GQRLKNCVRR HDVVGRLGGD EFAVVTFDVE HGKQIQALID
     HIRTALTEPI TVEGRRLRVD ASIGVVTARE GDERSAEDLL RDADVAMYQA KTRGRGRHEF
     FDVELRERVQ RQLRLEQDLR DSVRGGQLWV AYQPVVDLRT YQRVAVEGLL RWQHPVHGSI
     SPAEFIPLAE ESDLINLIGG HMMRTATREL ARRRLREGVR TRLTVNLSAR QLDDDSVVDA
     VNDALRSTGL PPGELCLEIT ESALMRDPGA AAEVLTSLRG LGVRLAIDDF GTGYSSLAQL
     WKLPLDTLKI DRSFVAGLDG PDQADAEAII KGIVTMAHSI GLTVIAEGTE NERQVAILRE
     LGCDQAQGFH FGRPAPADEV FGN
//