ID H5Y1P8_9FIRM Unreviewed; 442 AA.
AC H5Y1P8;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Fe-S oxidoreductase {ECO:0000313|EMBL:EHQ87801.1};
GN ORFNames=DesyoDRAFT_0621 {ECO:0000313|EMBL:EHQ87801.1};
OS Desulfosporosinus youngiae DSM 17734.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfosporosinus.
OX NCBI_TaxID=768710 {ECO:0000313|EMBL:EHQ87801.1, ECO:0000313|Proteomes:UP000005104};
RN [1] {ECO:0000313|EMBL:EHQ87801.1, ECO:0000313|Proteomes:UP000005104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17734 {ECO:0000313|EMBL:EHQ87801.1,
RC ECO:0000313|Proteomes:UP000005104};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Lu M., Land M.L., Hauser L., Pester M.,
RA Spring S., Ollivier B., Rattei T., Klenk H.-P., Wagner M., Loy A.,
RA Woyke T.J.;
RT "The Noncontiguous Finished genome of Desulfosporosinus youngiae DSM
RT 17734.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CM001441; EHQ87801.1; -; Genomic_DNA.
DR RefSeq; WP_007779264.1; NZ_CM001441.1.
DR AlphaFoldDB; H5Y1P8; -.
DR STRING; 768710.DesyoDRAFT_0621; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_021572_4_5_9; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000005104; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR030837; BzaD-like.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR NCBIfam; TIGR04385; B12_rSAM_cofa1; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF12; BLL1977 PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005104}.
FT DOMAIN 1..149
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 190..415
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 442 AA; 49997 MW; DEB388F0BD70329D CRC64;
MRILMIQTPS VEDFSQERVY PIGIVLLASR LQGYDHEVSI LDMNLERDPY GALKEKLLTF
QPEGIGLSLR NIDPLGNKTS SLVSPFIVTV QLIAAVLPQA WLIAGGTGFS LFPERLMMEI
PELDYGIVGE AEMTFPALLR SLDNPPSLPG LCRREGLKVH VSPPGADFDM SDYVPANRLL
LDPVLYQGIN NYVPTIGIEA KRGCALNCAY CVYPRLQGRR LRCRPAGAVV DEIEVLHKDY
GIKSFHFTDP VLNIPQGHLE GICEEILRRK LRIRWDGFMR EDQLNEKNVA LFERAGCECF
SFSPDGLCQE SLDSLNKNLS EAQILKAASL VAQTDTVSVY HFMVNVPGET EKTCEKSLRF
VERLYELHSR KRNLGTIILN NIRILPGTAI ERMARTQGVI DAETDLLYPT YYNPKPFNTL
RYKLETLQQC RNVFMWQEVK VK
//
