ID H6BM79_EXODN Unreviewed; 1046 AA.
AC H6BM79;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Transcriptional activator SPT7 {ECO:0000313|EMBL:EHY52015.1};
GN ORFNames=HMPREF1120_00237 {ECO:0000313|EMBL:EHY52015.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY52015.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY52015.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY52015.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH226130; EHY52015.1; -; Genomic_DNA.
DR RefSeq; XP_009152476.1; XM_009154228.1.
DR AlphaFoldDB; H6BM79; -.
DR STRING; 858893.H6BM79; -.
DR GeneID; 20304876; -.
DR VEuPathDB; FungiDB:HMPREF1120_00237; -.
DR eggNOG; KOG1472; Eukaryota.
DR HOGENOM; CLU_006198_0_0_1; -.
DR InParanoid; H6BM79; -.
DR OMA; YRRSEAK; -.
DR OrthoDB; 142354at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR CDD; cd05510; Bromo_SPT7_like; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR006565; BTP.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037782; Spt7.
DR PANTHER; PTHR47343; TRANSCRIPTIONAL ACTIVATOR SPT7; 1.
DR PANTHER; PTHR47343:SF1; TRANSCRIPTIONAL ACTIVATOR SPT7; 1.
DR Pfam; PF07524; Bromo_TP; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304}.
FT DOMAIN 347..417
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1024..1046
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..152
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..537
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1046 AA; 116819 MW; 743D8C6EA493118C CRC64;
MSLTWPPPNS QKPPDDEPLL HSLHRDNLNG LLRAPSRPHT PTLSRLRSLG GGSQSVQPAD
PEPSVEEDPQ VVRFRALFQE TESKLANLFN DVGEVVVPER SADLDAPALV DAPHVVEPAP
VAAPISKKRK LDDVDYDDYD DDDDDEEEEQ ETDAARASPL KDKPNKVHLV ADGTSSPVAR
PAPPSRSASD SVKAPPKTAA AKHTADAEDA RKKLEEAKRE EIEMVKTLSR TMFFTLEDDR
DAMLDQQRLD EAERRAEAEA EGQAKGQNAS AQQGSLSKAN LGASSLTLKN LIALLDEHRS
MVHATESELR ALMSEVRKNR SKWASEDKIG QEELYESAEK VLTELKAHTE HSFPFLNPVK
KKDAPDYYLV IKHPMDLGTM TKKLKQLAYR SKKEFVDDLY QIWKNCLKFN SNPDHVFRKH
ALFMQKETDK LVPLIPDIVI RDRAEVEAEE RRQQIANGEL DDGAEESDDE PIMSSRGRKA
PKKSAKKGGS TSRKAPPETT PIPETKPVLQ SISSVQQQGI RAESEAEGSQ GQSTPPPGIL
TPIGAHGPGS VAGTGSEAMD MDVPGLPSQA PLPEYEDEEY KLWKQKTKKD RAMVAAARHK
LFRGDKLNAE ETALLRTKAG MRRWQRMQQE ASGKDVSDFH GDGAEREQQG QTLAEGMEAE
EENLLPDYYD PLSAIPDLEP RLRWEQDAEG HVIEHCEEYL RLFPPKQFVA PESKLARKIQ
SNMRQMQETR KVVSKIGVVK QMQLQSQTYQ NQFQKYQPEP FVEADLPNHV MSDAGPLMAP
WVCRAAFQRS IGQIFFHAGF EEFQPSALDT MTDLAADFFQ RLCSTLVNYK EDYKVPVTTS
VPAPAGVRSK ANTVYQTPST DEEAILHTLH SSGISLSDLD TYAREDVDRM GARLAIMHER
MKGHLADLLR PALSEDTAHG QGTFADGGEQ YVGGDFAEDL DEDFFGFREL GLDKEFGMAS
LTVPFHILQN RLGMVNPQAN AEDAAEKMFK EPPRWPRISA DNVDEQIGLI RDFFKNLLRE
NNNRPLTEDL DLPPKQRPAA RSVTEP
//
