ID   H6BSF6_EXODN            Unreviewed;       816 AA.
AC   H6BSF6;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Glucan 1,3-beta-glucosidase {ECO:0000313|EMBL:EHY53362.1};
GN   ORFNames=HMPREF1120_01556 {ECO:0000313|EMBL:EHY53362.1};
OS   Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS   yeast) (Wangiella dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY53362.1, ECO:0000313|Proteomes:UP000007304};
RN   [1] {ECO:0000313|EMBL:EHY53362.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY53362.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   EMBL; JH226131; EHY53362.1; -; Genomic_DNA.
DR   RefSeq; XP_009153823.1; XM_009155575.1.
DR   AlphaFoldDB; H6BSF6; -.
DR   STRING; 858893.H6BSF6; -.
DR   GeneID; 20306195; -.
DR   VEuPathDB; FungiDB:HMPREF1120_01556; -.
DR   eggNOG; ENOG502QV54; Eukaryota.
DR   HOGENOM; CLU_002540_2_1_1; -.
DR   InParanoid; H6BSF6; -.
DR   OMA; IMSESQG; -.
DR   OrthoDB; 3714838at2759; -.
DR   Proteomes; UP000007304; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004650; F:polygalacturonase activity; IEA:InterPro.
DR   Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 2.
DR   InterPro; IPR024535; Pectate_lyase_SF_prot.
DR   InterPro; IPR012334; Pectin_lyas_fold.
DR   InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR   InterPro; IPR039279; QRT3-like.
DR   PANTHER; PTHR33928:SF2; PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR33928; POLYGALACTURONASE QRT3; 1.
DR   Pfam; PF12708; Pectate_lyase_3; 2.
DR   SUPFAM; SSF51126; Pectin lyase-like; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..816
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003603517"
FT   DOMAIN          49..285
FT                   /note="Pectate lyase superfamily protein"
FT                   /evidence="ECO:0000259|Pfam:PF12708"
FT   DOMAIN          441..512
FT                   /note="Pectate lyase superfamily protein"
FT                   /evidence="ECO:0000259|Pfam:PF12708"
SQ   SEQUENCE   816 AA;  88676 MW;  A9D745218FA59545 CRC64;
     MWSSCRHLWV VVLYLVHFTA CLSAQSTYWL ANKPNVGKVA FQDPSYPVFR NVKDYGATGG
     GVQDDSDAIN RAIAAPGNRC GGGNSTYGSF CQSSTVTPAL VYFPPGTYLV SKPLVMYYFT
     QMVGDAVNPP TIKVQSNFTN IVGLAVLDAN IYIPSGSGSE WYANQNNFYR QVRNFIIDMT
     TAPLKTAGIH WQVAQATSLQ NVVINMVAKD VVNNQQQGIY MENGSGGFFS DMVITGGAVG
     MYLGNQQFTT RKIHLDGCLT AIKMNFDWLW TFTQITITNS DVGIDMTNGG FSNQAIGSLV
     LLDSTISATQ GILTPYAPGY SSPQAAGTLI LENVDFTGSQ AAISAAGGTQ ARTVLAGGQF
     IPLFAQGNAW TTAGQALNGQ SFNGTTCTYA NSSQTAYSAQ ETTIQRQLAP IPRPSSLVDS
     NGQYIYRVKP QYETLQWSSF LSAKAHGLLG DGVTDDTVAM QALFNLAANT GQIVYFDKGA
     YIVSSTVTVP PNVKITGELL SIIMATGSFF NSEMNPKPMW KIGNPGDVGT VEISDLIFET
     KGPCPGAIMI EWNIKAAGPA LAGIWDAHWR IGGSAGTQLQ QDTCIKTPAT PIASGNAKLT
     NCIGAFLLLH VTPQADGYFE NTWGWVADHE LDMGTRDQVY IFNKGGFLIE SNNGPVWMYG
     TAAEHSVMYD YQFVNARNVF MGHIQHETAY FQGNPNALLP FTPQDSWHDP TYSDCVQPNC
     ARTWGLRFVN SSSIFMYGGG LYNFFENWNT QACLGTESCQ ERMVDIRNST DIYLWALSTK
     GSQFMISYEG TDVVPYSVNK ANFCETIALF ELAADQ
//