ID H6BTH2_EXODN Unreviewed; 607 AA.
AC H6BTH2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Auxin efflux carrier {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1120_02539 {ECO:0000313|EMBL:EHY54369.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY54369.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY54369.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY54369.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH226131; EHY54369.1; -; Genomic_DNA.
DR RefSeq; XP_009154830.1; XM_009156582.1.
DR AlphaFoldDB; H6BTH2; -.
DR STRING; 858893.H6BTH2; -.
DR GeneID; 20307178; -.
DR VEuPathDB; FungiDB:HMPREF1120_02539; -.
DR eggNOG; KOG2722; Eukaryota.
DR HOGENOM; CLU_026460_1_0_1; -.
DR InParanoid; H6BTH2; -.
DR OMA; IFVVQTF; -.
DR OrthoDB; 1430296at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR PANTHER; PTHR31794; AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG); 1.
DR PANTHER; PTHR31794:SF2; AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG); 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 54..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 226..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 67143 MW; 1A8ED80AEE9D2E5C CRC64;
MPLLDYLPSP ISFANRQFLG TLVERDQFTF TDNVIETLKK KGSRHGSHPD FGHLTLLVFE
AVLEVVCVSL PGYIVARQGM FDAESQKFLA NLNIILFTPC LIFTKLASQL TAEKLADLAI
IPIIFVVQTL VSYLCAWLIA KFLGFKKRQR NFLIAMGVFG NSNSLPISLV ISLSKTLKGL
HWDKVPNDND DEVAARGILY LLVFQQLGQL LRWSWGYNVL LAPPDTYTEE EGGTRNMSQL
EGGRSDYHDE SDSGDEQRRL LSPSYDDIAD SFEDFEDDAQ TRIGTESPTA SKSDGLKTPR
TPYNPSAESS RSSSRRNLQA AANAPNAPGN VMPTPPNGMV ASHHHLDYPA WLIHPDNQRY
DESCGGIMGH VNKGRNHVRC RCLMLRHQIR SKSTAAFESL PRSVQKGLSS ASYRLGRFFA
GVWEFMNPPL WAMLIAIIVA SVPQLQHVFF SEGTFVRNSV TRAVEQSGAV AVPLILVVLG
GNLAKNTIPR DESGTVTDPK EERKLLWASL VTRMVFPTMV MAPFVALVAK FAPVSIVGDK
IFVIVVYLLS GAPVALQIGQ ITTTNNVYPD LMSRILFQSY VVWILPSTLI LVLLALETVE
WASIGSA
//
