ID H6BU42_EXODN Unreviewed; 833 AA.
AC H6BU42;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=HMPREF1120_03749 {ECO:0000313|EMBL:EHY55619.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY55619.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY55619.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY55619.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH226132; EHY55619.1; -; Genomic_DNA.
DR RefSeq; XP_009156080.1; XM_009157832.1.
DR AlphaFoldDB; H6BU42; -.
DR STRING; 858893.H6BU42; -.
DR GeneID; 20308388; -.
DR VEuPathDB; FungiDB:HMPREF1120_03749; -.
DR eggNOG; KOG0118; Eukaryota.
DR HOGENOM; CLU_013226_1_0_1; -.
DR InParanoid; H6BU42; -.
DR OMA; LENQMDP; -.
DR OrthoDB; 2788138at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR23295:SF6; NEOSIN, ISOFORM A; 1.
DR PANTHER; PTHR23295; NUCLEAR RECEPTOR COACTIVATOR 5-RELATED; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 377..448
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 47..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 324..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 439..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..732
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 767..821
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..252
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..511
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..707
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 776..798
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 833 AA; 90995 MW; B4F0C5EDFA11EA5C CRC64;
MTETSPPPEA QRFGRSQTPE SPRPVHIPEP SNIPVLLNQM DPVFNDTATY NIPHNQTLSP
YSDSARGVHE PNSEEQDAVQ NFLRGAEEEN ARLERGGAQL PDTGGQTAQN DATIASNLLS
ALASHSAHQA LESHANASQA APGQTHSDVP QPGNESSISE ANANPSHGES SLQSHGEQNP
EQEPSVNPNT QSNTGGVDYQ SLLDTISQAA STAPPADSVS APATAPPAAD HGSSLSLPPI
PGLPPKPPVQ ASLPESPDYY TLPNSKSDVR EQYQSVNRDA LKTNGAEPAM PTQVQSMIQN
YPAHAPGTWE QNTALVPPTN PEAGFVGHPI QPPEPSGSTE STERPWSPRT QTLYDQFLED
ERRYVTEGIW DRFPLGSRLF VGNLASEKVT KRDLFHVFHK HGRLAQISIK QAYGFVQYLE
ASSCQAALQA EQGSEIRGRK IHLEVSKPQK NTRNQAQGNK RRRSRSPDRG TARQHDRYGR
HDFRDDRNRR DYRSTRSPSP RHFRGRDDYR GNAQSPRFAP DGRQGSPYAS TFPAAPPVAY
DDEATLPLPR RDPREVPDVQ ILVLEPSVAQ SFINWIEQGF RAKGLRASTI WLSPRLPLAA
VVKRQIIEGV QAVVKLTQSN QYNSKIPLQV FDRTTGASNV NFNEYVDLDV PVAADIVLHA
RQKERGMLPP PPQNFPPPPN YPQLPYGNQP PPQYPPQAHP PYGPAHHSPP QLQYGQQPHY
QPPLQTPVPP ATAAPNLQQL LANLRQPGDP HGSTTEAERN TANLASLLGR QPGPGQAGAY
PPPAAGAPQY PVPPLQQQQQ PAPAYGSVPA YGSGQPPQQN VQNIMETLAR YNR
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