ID H6BU43_EXODN Unreviewed; 331 AA.
AC H6BU43;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Isoflavone reductase {ECO:0000313|EMBL:EHY55620.1};
GN ORFNames=HMPREF1120_03750 {ECO:0000313|EMBL:EHY55620.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY55620.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY55620.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY55620.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH226132; EHY55620.1; -; Genomic_DNA.
DR RefSeq; XP_009156081.1; XM_009157833.1.
DR AlphaFoldDB; H6BU43; -.
DR STRING; 858893.H6BU43; -.
DR GeneID; 20308389; -.
DR VEuPathDB; FungiDB:HMPREF1120_03750; -.
DR eggNOG; ENOG502SAPA; Eukaryota.
DR HOGENOM; CLU_044876_2_0_1; -.
DR InParanoid; H6BU43; -.
DR OMA; IMMANDR; -.
DR OrthoDB; 1082618at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd05259; PCBER_SDR_a; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR008030; NmrA-like.
DR InterPro; IPR045312; PCBER-like.
DR PANTHER; PTHR47706:SF11; ISOFLAVONE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G12510); 1.
DR PANTHER; PTHR47706; NMRA-LIKE FAMILY PROTEIN; 1.
DR Pfam; PF05368; NmrA; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007304}.
FT DOMAIN 13..245
FT /note="NmrA-like"
FT /evidence="ECO:0000259|Pfam:PF05368"
SQ SEQUENCE 331 AA; 37086 MW; C09DEC6C82DE8CAE CRC64;
MQPYTTAQET RNILIIGSTG TVGTYITRAI IDARDNFDRI CVLTSEKTLV EKVQDIAALE
AWGVEIFTGG LDSERAVKKA YEGIDTIVSC VGRAGIEKQI NLITWAEQAG VRRFFASEYG
TDIEYWPESA REPPHQLKLK VRAHMKTMRR LEHTYLVTGP YSDLYFGTFK TRPELGEFDV
KAKKAVLLGD GDGPVSFTAM ADVGKFVVAA LVNNNASRNA TLIVHSFTAT PHEILAEYEA
QTGSTWEKSY TSLERLRQIE KEEYQVYSPL ATVVTLRRIW TEGGTLHKYY DETVLGHIET
ETLQSQVAAG IQKQLEGENH FPSLLRKLSL V
//
