ID   H6BWJ0_EXODN            Unreviewed;       538 AA.
AC   H6BWJ0;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Preprotein translocase YidC subunit {ECO:0000313|EMBL:EHY55236.1};
GN   ORFNames=HMPREF1120_03381 {ECO:0000313|EMBL:EHY55236.1};
OS   Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS   yeast) (Wangiella dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY55236.1, ECO:0000313|Proteomes:UP000007304};
RN   [1] {ECO:0000313|EMBL:EHY55236.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY55236.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC       Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC       {ECO:0000256|ARBA:ARBA00009877, ECO:0000256|RuleBase:RU003945}.
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DR   EMBL; JH226132; EHY55236.1; -; Genomic_DNA.
DR   RefSeq; XP_009155697.1; XM_009157449.1.
DR   AlphaFoldDB; H6BWJ0; -.
DR   STRING; 858893.H6BWJ0; -.
DR   GeneID; 20308020; -.
DR   VEuPathDB; FungiDB:HMPREF1120_03381; -.
DR   eggNOG; KOG1239; Eukaryota.
DR   HOGENOM; CLU_029282_5_0_1; -.
DR   InParanoid; H6BWJ0; -.
DR   OMA; WWASIVG; -.
DR   OrthoDB; 5395681at2759; -.
DR   Proteomes; UP000007304; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR   CDD; cd20069; 5TM_Oxa1-like; 1.
DR   InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR   InterPro; IPR028055; YidC/Oxa/ALB_C.
DR   NCBIfam; TIGR03592; yidC_oxa1_cterm; 1.
DR   PANTHER; PTHR12428:SF66; MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L; 1.
DR   PANTHER; PTHR12428; OXA1; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003945};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          201..391
FT                   /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02096"
FT   REGION          77..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          498..538
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        81..116
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   538 AA;  58408 MW;  12DF061972919599 CRC64;
     MSLSQGLRWS GRGIGNGRQR LVLGVRGVRN FSLHTSRVAR PQAKLTRTST GTVFQGSYQT
     RSLSLFGWGG KKAAEEVANT PPSSAAETAA QASGSPQNVV ETVKSVKASH ATSDAPDLTF
     THPHPVSPAE PEALRNLENE ILKPHGATPP ATETGDVPDL ASIPEGLGYL KDACGLDFGW
     GPTAILEVLL EHLHITAGLS WSASVIGLAI LVRTICLPAL VAGSDQSARM REVQGVLAPL
     REELSEALRN NNRQAAMEKQ AALRSINKEY GISLPKAFGG ILLQIPLGFG AFRLLRNAGT
     LPVPGFETEQ FLWLTNLSSA DPLYVLPILT GLMTYLNVKT NQRSTNMGNL ARIITPLLPI
     VSFAALSFQP AALQLYFLAN GIYTQMQSML ILNPRFRRML KLTPLPSSPS PSGPTTATAK
     PNFAKMKVGG QKPSVVEEQA PPTDRSVIDK GVDLVKEKGS QAIKGVFGNM NEAWQKEKMK
     RIEKERQEKR AATIAKYEAQ RRQDLEEQRY QRNAGAVGPM RINQTSEAPL SSKRREEK
//