ID H6C8P2_EXODN Unreviewed; 546 AA.
AC H6C8P2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=HemK protein {ECO:0000313|EMBL:EHY60469.1};
GN ORFNames=HMPREF1120_08430 {ECO:0000313|EMBL:EHY60469.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY60469.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY60469.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY60469.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH226136; EHY60469.1; -; Genomic_DNA.
DR RefSeq; XP_009160930.1; XM_009162682.1.
DR AlphaFoldDB; H6C8P2; -.
DR STRING; 858893.H6C8P2; -.
DR GeneID; 20313069; -.
DR VEuPathDB; FungiDB:HMPREF1120_08430; -.
DR eggNOG; KOG2904; Eukaryota.
DR HOGENOM; CLU_018398_0_3_1; -.
DR InParanoid; H6C8P2; -.
DR OrthoDB; 1121774at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR18895; HEMK METHYLTRANSFERASE; 1.
DR PANTHER; PTHR18895:SF74; MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007304}.
FT REGION 40..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..521
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 546 AA; 60606 MW; 2B211E8AE1944265 CRC64;
MPRLHPALIR QAATQNRYLP LLLRTCRDIG SAQNELRWLQ EHARDSGKTR PRARPETRGS
KSCTLRGGNQ RPSDGAGAGA GSSKQDTRGS PESIYPSIPR PHANNKKRHR LWSISRTDKT
SVRPSRLCGG QRPARRPKAN PAHNHDHGRY QTLRMLARNV ARRARGVPLQ YILGSQPFGN
LEILTHNKVL IPRPETETYT EHAARMILSW LHDTDTPTSS KAQSKPQGKP TPLRILDLCS
GTGCIALLLH SLLKPPETYA NASASAGFRD DNIADLDMDI EIAGIDISPD AIRLSRKNLH
HNMAQGLIHR DAVKEISFHQ LDILSLAKLD KCEMRRHLNR QVVKSHDYDS DTAVDSHAND
YNEWDIIISN PPYISPEDFR PGGKTESSVR KYEPKLALVP SPPPAGSVAT TDRKSATATA
TATTNLGDLF YRPLMDMMDG LGAKLLVMEV GDTEQAGRVH EEAMKRFDKK EKDALIESWK
DDGTEGLLAG GQAHGHRTSS TTPSDNRSCD SECNSNSKSN NVPDRAIVIY AGDLAKWRLS
RRWHPS
//
