ID   H6CAP1_EXODN            Unreviewed;       950 AA.
AC   H6CAP1;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=Chromosome transmission fidelity protein 18 {ECO:0000313|EMBL:EHY60838.1};
GN   ORFNames=HMPREF1120_08782 {ECO:0000313|EMBL:EHY60838.1};
OS   Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS   yeast) (Wangiella dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY60838.1, ECO:0000313|Proteomes:UP000007304};
RN   [1] {ECO:0000313|EMBL:EHY60838.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY60838.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the activator 1 small subunits family. CTF18
CC       subfamily. {ECO:0000256|ARBA:ARBA00043975}.
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DR   EMBL; JH226137; EHY60838.1; -; Genomic_DNA.
DR   RefSeq; XP_009161299.1; XM_009163051.1.
DR   AlphaFoldDB; H6CAP1; -.
DR   STRING; 858893.H6CAP1; -.
DR   GeneID; 20313421; -.
DR   VEuPathDB; FungiDB:HMPREF1120_08782; -.
DR   eggNOG; KOG1969; Eukaryota.
DR   HOGENOM; CLU_004894_0_0_1; -.
DR   InParanoid; H6CAP1; -.
DR   OMA; RWLKGWE; -.
DR   OrthoDB; 6297at2759; -.
DR   Proteomes; UP000007304; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR   PANTHER; PTHR23389:SF3; CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG; 1.
DR   Pfam; PF00004; AAA; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007304}.
FT   DOMAIN          273..437
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          1..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..75
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   950 AA;  105322 MW;  1C8E9FA4F28348C0 CRC64;
     MPFSSSPVLY PASSSPPPAL PIKKKRRLFQ PFPVEPPVKK PRIVGGFLED SDEEDSADVN
     KLGDIGRDEA SKEPTLPTIQ EHIGETLRAD NNGAQAQQPS ESTLPPLSRT LLRKISTRTV
     RICTTSGSSL HIPPRTKSEA LSYEQIIAQR SVSAPNRAKR SYYGVDIHKL VDEANTQRQL
     QEFEKQRRAE ELAKQPAEQV QEDHGSANLK TTRHQMWTEK YRAKKFTELV GDERTHRSIL
     RWLKSWDELV FPGSSKPKTL RIRDENELSH QQHKKILLLT GPPGLGKTTL AHVCAKQAGY
     EVLEINASDD RSRDVVKGRI KDALATETVR GIQEHGKARR SGRPVCVVVD EVDGVTTGSS
     SAGGEGGFIK ALIDLVQLDQ RNSTSATHDN QKLRKKKGDR FRMLRPLILV CNDVYAPSLR
     PLRTSSLAEI IHVRKAPIEK VIARMKTIFE KEHIPCDTDA VRRLCESVWG LAMRKQRVPG
     SRGSGEGDIR GVLVQGEWIA HKLRDRDACP RLTRQWLEPH LGDAQGCQGA LGRGGVREVV
     ERVFIEGAGL PNLSTILSTD DMRLVAESSS SGIGISDLRK RAAIRALREM IDTCGDHDRV
     VTDCFATYPT QPFQDDIQLS KPNASYDWLH FHDCLSSRVF SGQEWELAPY LSTSACGFHD
     LFAAVDKGSA TWNEEKIEED EVDPHPFSGP RADFAAYEAE KQNRTLLTEL QSKFSGPLLR
     LFPCIDTIAT ELLPNVGKML APDVKPVVIG GSGGSSSVAS VRKDTEKVCV RHAVRTMVAL
     EISLEKVRIE IEGGGPHSNG GFAYRMEPPL DTLLSFHLDK AGKPNVPIRY AVRQVLAQEL
     AKEKLLQNSL SRHARSVGLE VGNDIADGDD KENDGSERLK AAMSRSTELK RDFFGRIINE
     ARPVSAGKGS GGQMAKDKLR DGGRVWVSFH EGFSNAVRRP ITLKEFMEGF
//