ID H6CBH0_EXODN Unreviewed; 842 AA.
AC H6CBH0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=SulP family sulfate permease {ECO:0000313|EMBL:EHY61117.1};
GN ORFNames=HMPREF1120_09054 {ECO:0000313|EMBL:EHY61117.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY61117.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY61117.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY61117.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
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DR EMBL; JH226137; EHY61117.1; -; Genomic_DNA.
DR RefSeq; XP_009161578.1; XM_009163330.1.
DR AlphaFoldDB; H6CBH0; -.
DR STRING; 858893.H6CBH0; -.
DR GeneID; 20313693; -.
DR VEuPathDB; FungiDB:HMPREF1120_09054; -.
DR eggNOG; KOG0236; Eukaryota.
DR HOGENOM; CLU_003182_10_0_1; -.
DR InParanoid; H6CBH0; -.
DR OMA; TGPMSVT; -.
DR OrthoDB; 6913at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0098661; P:inorganic anion transmembrane transport; IEA:UniProtKB-UniRule.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR PANTHER; PTHR11814:SF263; SULFATE TRANSPORTER YPR003C-RELATED; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 237..255
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 267..287
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 320..340
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 352..371
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 405..424
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 436..457
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 496..515
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 536..556
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 576..596
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 632..660
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 690..822
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 842 AA; 92188 MW; 651752B672600B34 CRC64;
MATSRPSPSS TRGSSPPTSP RRPIPHSRGS SQHVPLYPSR LREATNMSPE ERMARSKSSE
EVAGGSGRDG KTVPTLLPGS DVPLIAEPEP LLQEGGNRDA QGLIEEPSLQ QVDARTSLLG
NYHHNRVCGL RDCNHGTFSP RAPSIRSGGS GADTPRPPFG APYPRAVDED GEQTGQSRGI
FGETLADSFF TSKSLYTTRW LAQKHGIKSP GFMYISYYIP FIRWVGQYRL SWLRGDFIAA
ITMASFYIPM SLSFASNLGH IPPINGLYSF VFNPLIYAFL GSCPQMVVGP EAAGSLLVGQ
VVKTCIKQGG STDDNDIVNA QVAGVVTAIA GSVIFVAGIC RLGFLDSVLS RPFLRGFISA
IGFVILVDQL IQELGLSEVA RQEGDASHGS SAQKLVFLFR NVGHSHRLTA AVSAVSFTII
MLFRSLKRAL QPRYQWVAYF PDRFLVVALS AIFAWQFGWD KQGLKVLGEV KPPGDGSPIP
FHWPFQFRHM KDIDTALSTS FLIALLGFFE SSVAAKSLGE GTHGLQGMTL SANREMIALG
TANIVGGCFG ALPAFGGYGR SKVNASTGGT TPMSSILLSF LTLICVLYLL PYFYYIPRGV
LSAMISVVAC SLIEECPHDI KFFLKIRGWT ELFLMGVIFL ATVFYSLSLG IALGVGLSLL
QLIRHATKPR IQILGKIPGT TNQFENAELS PENIEYIEGC LIVKIPEPLT FANTGELKTR
LRRLEQYGTN KAHPSLPPVR PAEHNRNVIF DVHGVTSIDG SGTQVFKEIV EDYVRRGIRV
IFCRLPHRRS KVFKSFERSG IIDLCGGYSH FVASVEDALR LSEAEDLEQF FDSRLNHHER
RT
//
