ID H6CGG3_9BACL Unreviewed; 362 AA.
AC H6CGG3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Xaa-Pro dipeptidase (X-Pro dipeptidase) {ECO:0000313|EMBL:EHS58191.1};
GN ORFNames=WG8_1451 {ECO:0000313|EMBL:EHS58191.1};
OS Paenibacillus sp. Aloe-11.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1050222 {ECO:0000313|EMBL:EHS58191.1, ECO:0000313|Proteomes:UP000005078};
RN [1] {ECO:0000313|Proteomes:UP000005078}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aloe-11 {ECO:0000313|Proteomes:UP000005078};
RX PubMed=22461553; DOI=10.1128/jb.00087-12;
RA Li N.Z., Xia T., Xu Y.L., Qiu R.R., Xiang H., He D., Peng Y.Y.;
RT "Genome Sequence of Paenibacillus sp. Strain Aloe-11, an Endophytic
RT Bacterium with Broad Antimicrobial Activity and Intestinal Colonization
RT Ability.";
RL J. Bacteriol. 194:2117-2118(2012).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
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DR EMBL; JH601050; EHS58191.1; -; Genomic_DNA.
DR RefSeq; WP_007429440.1; NZ_JH601050.1.
DR AlphaFoldDB; H6CGG3; -.
DR HOGENOM; CLU_017266_4_2_9; -.
DR Proteomes; UP000005078; Unassembled WGS sequence.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProt.
DR GO; GO:0008235; F:metalloexopeptidase activity; IEA:UniProt.
DR GO; GO:0046914; F:transition metal ion binding; IEA:UniProt.
DR CDD; cd01092; APP-like; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR001714; Pept_M24_MAP.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF10; DIPEPTIDASE YKVY-RELATED; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR PRINTS; PR00599; MAPEPTIDASE.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 5..134
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 143..344
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 362 AA; 39462 MW; 36E11AF57ABDCF8E CRC64;
MNDKITRLYN ELKSQAWDGL LVTDPKHIYY LTGFASEPHE RFLGLVLLRD QEPELIVPAL
DAEAAQAASS VTRISTHTDT DNPYDLLRQR AGSGVKAFAL EKEHVSVLRY EQLHTAIGAA
QYVDLGPVLQ EMRVRKTPEE VQRLKHAARL VEDALRHGLT HVREGVTEVE LVAEIEYQMK
KIGADGPSFD TTVLSGPKTA LPHGVPGTRK LQYGDLLMFD MGVYSDGYAS DITRTFAFGK
LSAELETIYN TVLRSNEAGI AATRPGVTCA SVDQAARAIV EAAGYGPAFN HRVGHGLGMS
VHEYPSVHGG NNDLLHEGFV FTIEPGIYVP GLGGVRIEDD VLVTSDGVEV LTSFPKELTV
LG
//
