ID H6L4R9_SAPGL Unreviewed; 1294 AA.
AC H6L4R9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Proprotein convertase p {ECO:0000313|EMBL:AFC25094.1};
GN OrderedLocusNames=SGRA_2365 {ECO:0000313|EMBL:AFC25094.1};
OS Saprospira grandis (strain Lewin).
OC Bacteria; Bacteroidota; Saprospiria; Saprospirales; Saprospiraceae;
OC Saprospira.
OX NCBI_TaxID=984262 {ECO:0000313|EMBL:AFC25094.1, ECO:0000313|Proteomes:UP000007519};
RN [1] {ECO:0000313|EMBL:AFC25094.1, ECO:0000313|Proteomes:UP000007519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lewin {ECO:0000313|EMBL:AFC25094.1,
RC ECO:0000313|Proteomes:UP000007519};
RX PubMed=22675601; DOI=10.4056/sigs.2445005;
RA Saw J.H., Yuryev A., Kanbe M., Hou S., Young A.G., Aizawa S., Alam M.;
RT "Complete genome sequencing and analysis of Saprospira grandis str. Lewin,
RT a predatory marine bacterium.";
RL Stand. Genomic Sci. 6:84-93(2012).
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DR EMBL; CP002831; AFC25094.1; -; Genomic_DNA.
DR RefSeq; WP_015692709.1; NC_016940.1.
DR STRING; 984262.SGRA_2365; -.
DR KEGG; sgn:SGRA_2365; -.
DR eggNOG; COG1470; Bacteria.
DR eggNOG; COG4935; Bacteria.
DR HOGENOM; CLU_006954_0_0_10; -.
DR Proteomes; UP000007519; Chromosome.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR001590; Peptidase_M12B.
DR InterPro; IPR026444; Secre_tail.
DR NCBIfam; TIGR04183; Por_Secre_tail; 1.
DR PANTHER; PTHR11905; ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN; 1.
DR PANTHER; PTHR11905:SF159; MIND-MELD, ISOFORM J; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF18962; Por_Secre_tail; 1.
DR Pfam; PF13583; Reprolysin_4; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR PROSITE; PS50215; ADAM_MEPRO; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000007519}.
FT DOMAIN 204..415
FT /note="Peptidase M12B"
FT /evidence="ECO:0000259|PROSITE:PS50215"
FT DOMAIN 754..845
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 831..989
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
SQ SEQUENCE 1294 AA; 136902 MW; 8C85C487DB3798E4 CRC64;
MRILSTIFLS CLMLTGLWAQ GQELWQSQTE ASIPVLGVRY IQPQAAAYYQ LDLDQLQQLL
DAAPMEFTPI AQMSQTLISL PMPDGSMQSF DIQESPIMEA ALSERFPDIQ TFNGRGVTDP
SKSLRFDLTP AGFHAMILQA DGPTIFIDPV YFKGDKRYYQ VYYRSDFRST VAKNFSCQTE
TPMSKGQTNK RPLLPKSFGS CELRTYRLAL AATGEYTQFH GGTVADALAA QVVSMNRVNA
VYERDLAVRM VIVADNYKII YTNGSTDPYS NASGGAMLGE NQTICDDSIG TANYDIGHVF
STGGGGVAYL QSVCNNNKAG GVTGSANPIG DPFDIDYVAH EMGHQFGANH TQNNACNRNG
ATAMEPGSAS TIMGYAGICA PNVQNNSDDH FHGVSLEEMG AFITSSGHSC PTTTPLANNS
PVVNNSTNTL VIPANTPFFL TGDAQDQDTA DVLTYCWEQM DNQTATMPPL PTATVGPSFR
SISPSSNPTR YFPNLADLSA GISPSWEVLS SVSRSYNFRL TVRDNASGGG CTDHVDLSVN
VDANSGPFII NYPSATGISW IGTTQETVQW DVANTNNAPV NCTLVDILLS TDGGLTYPTV
LATATPNDGS EVITVPNTPS STCRIMVRAS GGNFFDISDN DFEITGASFG YNLSVAMDSL
AGCPNSNGSY FVTVTGLLGY TDPVQLSLTG LPTGATASFG NANITPSDTT TLSIALGNAA
AGDYSLNLIA QNASDTQSLN LMLSILDGSL AAPSPQQPAN QAQGVISPAN FSWTASSSAG
QSFGIEIATD ANFTNIVESA SNLSSPSYTS GNLSANTTYY WRVSASNACS NSPNSAVFEF
TTADCSIYAA ADLPIAIPAS GAPTISSNIN IPNAGSIIDL NVVNLTGTHS WVSDLTFVLS
SPSNSSATLF AQICGGDDDF DVNFDDAAAS SQLPCPPVGG GTYQAEDLLS IFNGQNPAGS
WTLSVSDGAN QDGGSLDSWG LQVCVAAPSN ANDAAILDIT NLSGRYCNQG DFVPEIEIAN
FGASALTSLT INYTLDGGSP QSFNWSGNLA TNATATVSLP QISVAAGTHS YSVELTAPNG
QTDGDLSNNT AATSFTYVSP GQDVTVAITT DNFGSETTWE ILNAQSFPIA SGGPYQDGTA
NQTFSLANCL PEGCYTFVIY DSYGDGLNDG QNTGNFLLSD TSGTVLAEMG ANFTDSTSRA
FCIQPTAVEA IDGLTLFEVF PNPASQTCFV QLQLEQAEQA QLSLVNTLGQ ELRQYTVDQN
WQQQIDLRDL PAGVYYLRLQ LDQKQQSQKL IIHR
//
