ID   H6L578_SAPGL            Unreviewed;       398 AA.
AC   H6L578;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=N-acyl-L-amino acid amidohydrolase {ECO:0000313|EMBL:AFC23992.1};
DE            EC=3.5.1.32 {ECO:0000313|EMBL:AFC23992.1};
GN   Name=hipO {ECO:0000313|EMBL:AFC23992.1};
GN   OrderedLocusNames=SGRA_1257 {ECO:0000313|EMBL:AFC23992.1};
OS   Saprospira grandis (strain Lewin).
OC   Bacteria; Bacteroidota; Saprospiria; Saprospirales; Saprospiraceae;
OC   Saprospira.
OX   NCBI_TaxID=984262 {ECO:0000313|EMBL:AFC23992.1, ECO:0000313|Proteomes:UP000007519};
RN   [1] {ECO:0000313|EMBL:AFC23992.1, ECO:0000313|Proteomes:UP000007519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lewin {ECO:0000313|EMBL:AFC23992.1,
RC   ECO:0000313|Proteomes:UP000007519};
RX   PubMed=22675601; DOI=10.4056/sigs.2445005;
RA   Saw J.H., Yuryev A., Kanbe M., Hou S., Young A.G., Aizawa S., Alam M.;
RT   "Complete genome sequencing and analysis of Saprospira grandis str. Lewin,
RT   a predatory marine bacterium.";
RL   Stand. Genomic Sci. 6:84-93(2012).
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DR   EMBL; CP002831; AFC23992.1; -; Genomic_DNA.
DR   RefSeq; WP_015691637.1; NC_016940.1.
DR   AlphaFoldDB; H6L578; -.
DR   STRING; 984262.SGRA_1257; -.
DR   KEGG; sgn:SGRA_1257; -.
DR   eggNOG; COG1473; Bacteria.
DR   HOGENOM; CLU_023257_1_1_10; -.
DR   OrthoDB; 9776731at2; -.
DR   Proteomes; UP000007519; Chromosome.
DR   GO; GO:0047980; F:hippurate hydrolase activity; IEA:UniProtKB-EC.
DR   CDD; cd03886; M20_Acy1; 1.
DR   Gene3D; 3.30.70.360; -; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR017439; Amidohydrolase.
DR   InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR   InterPro; IPR002933; Peptidase_M20.
DR   InterPro; IPR011650; Peptidase_M20_dimer.
DR   NCBIfam; TIGR01891; amidohydrolases; 1.
DR   PANTHER; PTHR11014:SF63; METALLOPEPTIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G09600)-RELATED; 1.
DR   PANTHER; PTHR11014; PEPTIDASE M20 FAMILY MEMBER; 1.
DR   Pfam; PF07687; M20_dimer; 1.
DR   Pfam; PF01546; Peptidase_M20; 1.
DR   PIRSF; PIRSF005962; Pept_M20D_amidohydro; 1.
DR   SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AFC23992.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007519}.
FT   DOMAIN          194..287
FT                   /note="Peptidase M20 dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF07687"
SQ   SEQUENCE   398 AA;  44340 MW;  3093E3EB538E0880 CRC64;
     MIKIDKIKQL AQEQLEQWIS IRRHLHQYPE LSFEEWETAN YIASCLDRWG ISYQRGMVKT
     GIFAQIEGKN PDAACITLRA DIDALPIQEQ TGLPFSSKNE GRMHACGHDV HTTSLLATAF
     ILNELKEEFE GRVQLIFQPG EELLPGGASQ VLAEGWLDQS RDFPILGQHV EPGLPAGQVG
     FHPGPFMASA DELYLSVYGK GGHAARPQDC NDVVLIASHL VIALQQLISR FRDPLQPSVL
     SFGKMNTAGG ATNVLPERID LEGTFRAFNE EWRAEAHQKM QQLCQQMAQS MGGRAELEIR
     KGYPYLHNEE SLTHSLMQAA RDYVGKDNLV LLPQRMGAED FGFYAQQMPA CFYRLGTGIG
     PGLHHPKFSP DEKTALPLGA GLMAYLALFQ LNQQIKKA
//