ID H6LHA3_ACEWD Unreviewed; 798 AA.
AC H6LHA3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=DNA internalization-like competence protein/Rec2 {ECO:0000313|EMBL:AFA48441.1};
GN Name=comEC {ECO:0000313|EMBL:AFA48441.1};
GN OrderedLocusNames=Awo_c16590 {ECO:0000313|EMBL:AFA48441.1};
OS Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655
OS / WB1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Acetobacterium.
OX NCBI_TaxID=931626 {ECO:0000313|EMBL:AFA48441.1, ECO:0000313|Proteomes:UP000007177};
RN [1] {ECO:0000313|Proteomes:UP000007177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1
RC {ECO:0000313|Proteomes:UP000007177};
RA Poehlein A., Schmidt S., Kaster A.-K., Goenrich M., Vollmers J.,
RA Thuermer A., Gottschalk G., Thauer R.K., Daniel R., Mueller V.;
RT "Complete genome sequence of Acetobacterium woodii.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFA48441.1, ECO:0000313|Proteomes:UP000007177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1
RC {ECO:0000313|Proteomes:UP000007177};
RX PubMed=22479398; DOI=10.1371/journal.pone.0033439;
RA Poehlein A., Schmidt S., Kaster A.K., Goenrich M., Vollmers J., Thurmer A.,
RA Bertsch J., Schuchmann K., Voigt B., Hecker M., Daniel R., Thauer R.K.,
RA Gottschalk G., Muller V.;
RT "An ancient pathway combining carbon dioxide fixation with the generation
RT and utilization of a sodium ion gradient for ATP synthesis.";
RL PLoS ONE 7:E33439-E33439(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002987; AFA48441.1; -; Genomic_DNA.
DR RefSeq; WP_014356044.1; NC_016894.1.
DR AlphaFoldDB; H6LHA3; -.
DR STRING; 931626.Awo_c16590; -.
DR KEGG; awo:Awo_c16590; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR HOGENOM; CLU_010363_2_1_9; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000007177; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007177};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 547..752
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 798 AA; 89009 MW; 98577BB0D4C378DC CRC64;
MKRPLLWGFA ALSLGVVTSF YRAPLWLILI FSCLLVVMPF FIKQVKNSQV FFILGLFCLG
LVLGSTTFLQ SDELEPFYEK EVSVLGVVTD YPISKAGQLA IKLKTKEISS SNDLKKQLKK
QIGLKTTIYL ESDNNSKIKS SNLNYIPGDI LLLKGNLSEP AGKRNPGGFD YDLYLKSQSI
DALLSVRPEN IELIGQETSI YDQILKIKRT LEDQSDAYLS EDVSDLLKGV VFGEKDISNE
LSQRFQDAGV SHVLAVSGLH VGYLFVALSF LLMTMKIRRQ YWIIFLAPML FFYIALTGFA
PSVIRASIML LCLTLGQGIH REHDALNQLS LAGLIIIWIW PAQLFQAGFQ LSMGAVLGIV
IFYQPLLYRY EKIRNHKRVK NKITSGPLMQ GLILTFCATV GTLPILLYHF KSFTLISFFA
NIVVVPLIGI FLLTSLVFLL LISCFPFLGP VLSIPVGFLG ESIVVMLMGI NDVGDTLGFL
WINRGGFTVA EIGLFLWAIF LISGYFYLKL PRVKQLVTAV GMGLILILMV SLFLPKNLVV
TILDVGQGDS ILIETPEGHH YLVDGGGYLF EKSTTISENV LYPVLYSKNI KKLDGVFLTH
NHVDHSQGIE ELIFDGYPVE NLFMSIQTNN EKLLQQQMAP VILLKKGSVI EEPGGITIEV
YNPEGKINPK DDDEQNNTSL VMRLSYKNTN LLLCGDIEAA VESQLAEILA AESKKRDFQM
IKIPHHGSKT SSTPAFIQAI EPEMAVISVG AHNLFGHPSD EVLHRLEDND ITTLRTDKNG
AIEITSNGEW IHYKNYQN
//
