ID H6LHY1_ACEWD Unreviewed; 450 AA.
AC H6LHY1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=4-aminobutyrate aminotransferase GabT2 {ECO:0000313|EMBL:AFA48511.1};
DE EC=2.6.1.19 {ECO:0000313|EMBL:AFA48511.1};
GN Name=gabT2 {ECO:0000313|EMBL:AFA48511.1};
GN OrderedLocusNames=Awo_c17310 {ECO:0000313|EMBL:AFA48511.1};
OS Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655
OS / WB1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Acetobacterium.
OX NCBI_TaxID=931626 {ECO:0000313|EMBL:AFA48511.1, ECO:0000313|Proteomes:UP000007177};
RN [1] {ECO:0000313|Proteomes:UP000007177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1
RC {ECO:0000313|Proteomes:UP000007177};
RA Poehlein A., Schmidt S., Kaster A.-K., Goenrich M., Vollmers J.,
RA Thuermer A., Gottschalk G., Thauer R.K., Daniel R., Mueller V.;
RT "Complete genome sequence of Acetobacterium woodii.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFA48511.1, ECO:0000313|Proteomes:UP000007177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1
RC {ECO:0000313|Proteomes:UP000007177};
RX PubMed=22479398; DOI=10.1371/journal.pone.0033439;
RA Poehlein A., Schmidt S., Kaster A.K., Goenrich M., Vollmers J., Thurmer A.,
RA Bertsch J., Schuchmann K., Voigt B., Hecker M., Daniel R., Thauer R.K.,
RA Gottschalk G., Muller V.;
RT "An ancient pathway combining carbon dioxide fixation with the generation
RT and utilization of a sodium ion gradient for ATP synthesis.";
RL PLoS ONE 7:E33439-E33439(2012).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC aminotransferase family. {ECO:0000256|ARBA:ARBA00008954,
CC ECO:0000256|RuleBase:RU003560}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002987; AFA48511.1; -; Genomic_DNA.
DR RefSeq; WP_014356111.1; NC_016894.1.
DR AlphaFoldDB; H6LHY1; -.
DR STRING; 931626.Awo_c17310; -.
DR KEGG; awo:Awo_c17310; -.
DR eggNOG; COG0160; Bacteria.
DR HOGENOM; CLU_016922_10_0_9; -.
DR OrthoDB; 9807885at2; -.
DR Proteomes; UP000007177; Chromosome.
DR GO; GO:0034386; F:4-aminobutyrate:2-oxoglutarate transaminase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009448; P:gamma-aminobutyric acid metabolic process; IEA:InterPro.
DR CDD; cd00610; OAT_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR004632; 4NH2But_aminotransferase_bac.
DR InterPro; IPR005814; Aminotrans_3.
DR InterPro; IPR049704; Aminotrans_3_PPA_site.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR00700; GABAtrnsam; 1.
DR PANTHER; PTHR11986; AMINOTRANSFERASE CLASS III; 1.
DR PANTHER; PTHR11986:SF58; LEUCINE_METHIONINE RACEMASE; 1.
DR Pfam; PF00202; Aminotran_3; 1.
DR PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:AFA48511.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|RuleBase:RU003560};
KW Reference proteome {ECO:0000313|Proteomes:UP000007177};
KW Transferase {ECO:0000313|EMBL:AFA48511.1}.
SQ SEQUENCE 450 AA; 49005 MW; B9D01469DE3D4959 CRC64;
MLKNELPKII TAQVPGPKAQ AIIERREKAV PAAIKCVYPV VIEKGEGAMV EDVDGNQFID
WVGGVGVLNI GYSHPEIVAA VKDQSEKYFH GMFNIVTHEG YVELAEKMNA IVPVKGNEKM
TFFANSGAEA DENAVKVAKA FTKRPNIIVF SGAFHGRTML TMTMTSKKAY AYGLGPFPDG
VYRAQFPYLY RTPGEMTESA AIDYYTESIY KVFEECSPAE YVAAIVVEPL QGEGGFIPAP
IEWVKAVRKI CDEKGILLIA DEVQTGFCRT GKMFASEYWQ AVDAQPDIIT SAKSIAAGLP
ISAITARKEI MESVKGGTIG GTFCGNPLAC AAALKVIEIM QRDHMDERAA EIGKKVIDRF
NQWQTKYDVI GDIRGLGAMI GIEFVKDTST KEPYPELVAA VVNEAAQNGL IIESAGVYGN
VIRFLAPLVI TETQLDAGLD IFEKAIAKCI
//
