ID H6MWG7_GORPV Unreviewed; 273 AA.
AC H6MWG7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Enoyl-CoA hydratase domain-containing protein 3, mitochondrial {ECO:0000256|ARBA:ARBA00040545};
GN OrderedLocusNames=GPOL_c31570 {ECO:0000313|EMBL:AFA74172.1};
OS Gordonia polyisoprenivorans (strain DSM 44266 / VH2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1112204 {ECO:0000313|EMBL:AFA74172.1, ECO:0000313|Proteomes:UP000009154};
RN [1] {ECO:0000313|EMBL:AFA74172.1, ECO:0000313|Proteomes:UP000009154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44266 / VH2 {ECO:0000313|Proteomes:UP000009154};
RX PubMed=22327575; DOI=10.1128/AEM.07969-11;
RA Hiessl S., Schuldes J., Thurmer A., Halbsguth T., Broker D., Angelov A.,
RA Liebl W., Daniel R., Steinbuchel A.;
RT "Involvement of two latex-clearing proteins during rubber degradation and
RT insights into the subsequent degradation pathway revealed by the genome
RT sequence of Gordonia polyisoprenivorans strain VH2.";
RL Appl. Environ. Microbiol. 78:2874-2887(2012).
CC -!- FUNCTION: May play a role in fatty acid biosynthesis and insulin
CC sensitivity. {ECO:0000256|ARBA:ARBA00037410}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
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DR EMBL; CP003119; AFA74172.1; -; Genomic_DNA.
DR RefSeq; WP_014360642.1; NC_016906.1.
DR AlphaFoldDB; H6MWG7; -.
DR STRING; 1112204.GPOL_c31570; -.
DR KEGG; gpo:GPOL_c31570; -.
DR eggNOG; COG1024; Bacteria.
DR HOGENOM; CLU_009834_7_3_11; -.
DR Proteomes; UP000009154; Chromosome.
DR GO; GO:0004300; F:enoyl-CoA hydratase activity; IEA:UniProtKB-EC.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR PANTHER; PTHR43602; -; 1.
DR PANTHER; PTHR43602:SF1; ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:AFA74172.1};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000009154};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 273 AA; 28853 MW; F665EF5422F9E82C CRC64;
MTHTAQPATG VGTGSSDPDP VEVVVEAPLG IVTLTRPRRR NPLSTETMRA VTAALRTLGS
DDAVRVVVIR AHGPAFSAGH DLSELVDRTL DDERAVFDTC VEMMAAVHEL DRPVIAEVAG
AAFAAGCQLV ATCDLAVAAT TATFSTPGVR IGLFCSTPMV ALTRAIGRKR AMKMLLTGDA
IDADTAADWG LVNDVVSPDE LATTVRELAL RIAGSSASTL AIGKRAFYQQ IDETETRAYE
LMAETMATNA MTCDAQEGMS AFLAKRAPVW TDR
//
