ID H6MYR7_GORPV Unreviewed; 460 AA.
AC H6MYR7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Putative transcriptional regulator, GntR family with aminotransferase domain {ECO:0000313|EMBL:AFA71945.1};
GN OrderedLocusNames=GPOL_c08800 {ECO:0000313|EMBL:AFA71945.1};
OS Gordonia polyisoprenivorans (strain DSM 44266 / VH2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1112204 {ECO:0000313|EMBL:AFA71945.1, ECO:0000313|Proteomes:UP000009154};
RN [1] {ECO:0000313|EMBL:AFA71945.1, ECO:0000313|Proteomes:UP000009154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44266 / VH2 {ECO:0000313|Proteomes:UP000009154};
RX PubMed=22327575; DOI=10.1128/AEM.07969-11;
RA Hiessl S., Schuldes J., Thurmer A., Halbsguth T., Broker D., Angelov A.,
RA Liebl W., Daniel R., Steinbuchel A.;
RT "Involvement of two latex-clearing proteins during rubber degradation and
RT insights into the subsequent degradation pathway revealed by the genome
RT sequence of Gordonia polyisoprenivorans strain VH2.";
RL Appl. Environ. Microbiol. 78:2874-2887(2012).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; CP003119; AFA71945.1; -; Genomic_DNA.
DR RefSeq; WP_014358885.1; NC_016906.1.
DR AlphaFoldDB; H6MYR7; -.
DR STRING; 1112204.GPOL_c08800; -.
DR KEGG; gpo:GPOL_c08800; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_2_0_11; -.
DR Proteomes; UP000009154; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:AFA71945.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000009154};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:AFA71945.1}.
FT DOMAIN 19..87
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 460 AA; 48887 MW; A6CA4E032AE07614 CRC64;
MTVHDPATEV TPQRIVIDDP TPAGIAGAIG RMIRNGELVP GDRLPTVRDL SAQLGVSPAT
VSYGWKALSR SGLVVSRGRS GTFVADGAVS PEVPRVSRTA TMARTHGSIG LDLSKGSPDP
ELLPELKAAL SNVAERAATT SYHDHPVVPE LGDLLRTRWP SKAQALTVVD GALDAVTRSL
QAVTRFGDRV IVEDPTFPQF LDLLDTLGLQ HIPVPVDRHG PDPDAFARAM AQAPTVALLQ
PRAHNPTGVS MTAARARDLA RAVRGTRCVV IEDDHSGAAV AAPDISLGRW LPDQVVHVRS
FSKSHGPDLR IAAMTGPREV IDRVTATRML GPGWTPRLLQ RVLYELLTDE ASVAAVDNAR
AAYRSRRAAL VEALADKGID VGGTDGLNVW VPVADERNAL IHLAANGIQV APGDPFIVEP
QRGGDHVRVT IATLRDDVER VAATLAAAAS GNQADFYPLR
//
