ID H6N4I2_GORPV Unreviewed; 458 AA.
AC H6N4I2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Shikimate transporter ShiA {ECO:0000313|EMBL:AFA73564.1};
GN Name=shiA {ECO:0000313|EMBL:AFA73564.1};
GN OrderedLocusNames=GPOL_c25350 {ECO:0000313|EMBL:AFA73564.1};
OS Gordonia polyisoprenivorans (strain DSM 44266 / VH2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1112204 {ECO:0000313|EMBL:AFA73564.1, ECO:0000313|Proteomes:UP000009154};
RN [1] {ECO:0000313|EMBL:AFA73564.1, ECO:0000313|Proteomes:UP000009154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44266 / VH2 {ECO:0000313|Proteomes:UP000009154};
RX PubMed=22327575; DOI=10.1128/AEM.07969-11;
RA Hiessl S., Schuldes J., Thurmer A., Halbsguth T., Broker D., Angelov A.,
RA Liebl W., Daniel R., Steinbuchel A.;
RT "Involvement of two latex-clearing proteins during rubber degradation and
RT insights into the subsequent degradation pathway revealed by the genome
RT sequence of Gordonia polyisoprenivorans strain VH2.";
RL Appl. Environ. Microbiol. 78:2874-2887(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003119; AFA73564.1; -; Genomic_DNA.
DR AlphaFoldDB; H6N4I2; -.
DR STRING; 1112204.GPOL_c25350; -.
DR KEGG; gpo:GPOL_c25350; -.
DR eggNOG; COG0477; Bacteria.
DR HOGENOM; CLU_001265_39_5_11; -.
DR Proteomes; UP000009154; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR43045; SHIKIMATE TRANSPORTER; 1.
DR PANTHER; PTHR43045:SF1; SHIKIMATE TRANSPORTER; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009154};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 28..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..442
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 458 AA; 48265 MW; D78EF0BB55ACB1A2 CRC64;
MTTEHNVSAP PDTGEEVERM TPAARRALLG AAAGTLIEWF DYALYGSLAA ILARELFFPE
VSPGLGVLAA FGAYGVAFVV RPLGGLVIGR IGDRYGRKPG LVLSLTIMGL STFAIAFLPT
FAVAGYWAAV LLVVLRLLQG FGAGAENAGA LALVAEYAPL RQRGFYTALM QSVVLVGVLL
ATVAFLLVSA LPREAQLSWG WRVPFLSAGL MLLVAFYIRS RLEESPEFVA VAEKTRNAGS
KPVQPIALLF GTMKARLVAM FVIISAYNVF AACLTSFVSS YLRNTVEVSA MQALGAVSVG
TLFGAVAAPA FGAACDRYGF RPVWRVAAWT TIPGVFAMFF GLSTGNFWIA ALSISLAYVI
PYAAGAGAFP GLLANVFPAQ VRFSGIATVR EFSAALVAGT FPFIATALVL ASGGAPWLVA
GYIAIWSVLG LLAIGWLGHH SETPATRNLM VDQSEPTS
//
