ID   H6QYC3_NOCCG            Unreviewed;       296 AA.
AC   H6QYC3;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=LysR-family transcriptional regulator {ECO:0000313|EMBL:CCF62769.1};
GN   OrderedLocusNames=NOCYR_1983 {ECO:0000313|EMBL:CCF62769.1};
OS   Nocardia cyriacigeorgica (strain GUH-2).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF62769.1, ECO:0000313|Proteomes:UP000008190};
RN   [1] {ECO:0000313|EMBL:CCF62769.1, ECO:0000313|Proteomes:UP000008190}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GUH-2 {ECO:0000313|EMBL:CCF62769.1,
RC   ECO:0000313|Proteomes:UP000008190};
RX   PubMed=22461543; DOI=10.1128/JB.00161-12;
RA   Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA   Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA   Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA   Richard Y., Cournoyer B., Blaha D.;
RT   "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT   cyriacigeorgica GUH-2.";
RL   J. Bacteriol. 194:2098-2099(2012).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
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DR   EMBL; FO082843; CCF62769.1; -; Genomic_DNA.
DR   RefSeq; WP_014350234.1; NC_016887.1.
DR   AlphaFoldDB; H6QYC3; -.
DR   STRING; 1127134.NOCYR_1983; -.
DR   KEGG; ncy:NOCYR_1983; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_4_11; -.
DR   OrthoDB; 3176554at2; -.
DR   Proteomes; UP000008190; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08414; PBP2_LTTR_aromatics_like; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30346:SF0; HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR; 1.
DR   PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008190}.
FT   DOMAIN          3..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   296 AA;  32544 MW;  DA375E51B90ACD27 CRC64;
     MDVDTRLLRY FAAVAEEGNL TRAAQRLYVS QPSLTKQIRR LEELLGVSLF VRSRTGMGLT
     EAGNALARSV PPLLTDWQRA VTEVKNAAAE QDRVLRVGFL ASAANEATPD IIAAFGETRP
     GWRVEMRQSS WWDPTAGLAA GEVDVALLRV PFPDQHAWGV EVLLTELRGV MLPSTHPLAG
     AEVIAFEQLW DEPFISAPEA TGAWRDYWLA VEERQGHPVR IGAVTEHTDE WLSAIANGYG
     VALAPESAAR YFQRPGVVYR PVTGIAPTQV AVAWDRALAS SAVHDFVACC LRFRQD
//