ID H6R1V2_NOCCG Unreviewed; 312 AA.
AC H6R1V2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Beta lactamase {ECO:0000313|EMBL:CCF63031.1};
GN OrderedLocusNames=NOCYR_2254 {ECO:0000313|EMBL:CCF63031.1};
OS Nocardia cyriacigeorgica (strain GUH-2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF63031.1, ECO:0000313|Proteomes:UP000008190};
RN [1] {ECO:0000313|EMBL:CCF63031.1, ECO:0000313|Proteomes:UP000008190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GUH-2 {ECO:0000313|EMBL:CCF63031.1,
RC ECO:0000313|Proteomes:UP000008190};
RX PubMed=22461543; DOI=10.1128/JB.00161-12;
RA Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA Richard Y., Cournoyer B., Blaha D.;
RT "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT cyriacigeorgica GUH-2.";
RL J. Bacteriol. 194:2098-2099(2012).
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DR EMBL; FO082843; CCF63031.1; -; Genomic_DNA.
DR RefSeq; WP_014350491.1; NC_016887.1.
DR AlphaFoldDB; H6R1V2; -.
DR STRING; 1127134.NOCYR_2254; -.
DR KEGG; ncy:NOCYR_2254; -.
DR eggNOG; COG2367; Bacteria.
DR HOGENOM; CLU_031960_3_0_11; -.
DR OrthoDB; 33989at2; -.
DR Proteomes; UP000008190; Chromosome.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF4; SLR0121 PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008190}.
FT DOMAIN 38..278
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 312 AA; 33020 MW; 06CD8A8B0585AF66 CRC64;
MSHARYPALP LGTDTGEVTD RIRAVFADAG CTGWLHARRC GSPAEISVDA HDRVVIASVY
KLVLLVAFCR RVDAGLIDPR APLTVHPADC TPGPTGIAAL HDPVTMSRRD LATSMMTVSD
NAAADVLLGE IGLGAVEELL TELGLTETRI VGGTADVHRS LVRDTDTHST AEAFAALADN
DEAWSVSAYD PSYASATTPE EMTRFLDLIW AGGVLSPEQT GFVRAVMGKQ VWPHRIASAF
PHRGVGVAGK TGTIGVIRNE VAVVEFPDEY PVAVAVFTRA ARADPQLAVV DAAIAEAARI
AVTALRHPLT QD
//
