ID H6UQ41_9NEOP Unreviewed; 216 AA.
AC H6UQ41;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Isocitrate dehydrogenase {ECO:0000313|EMBL:AEZ54629.1};
DE Flags: Fragment;
GN Name=IDH {ECO:0000313|EMBL:AEZ54629.1};
OS Gonodonta milla.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Erebidae; Erebinae; Gonodonta.
OX NCBI_TaxID=1137971 {ECO:0000313|EMBL:AEZ54629.1};
RN [1] {ECO:0000313|EMBL:AEZ54629.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=22796530; DOI=10.1016/j.ympev.2012.06.029;
RA Zaspel J.M., Zahiri R., Hoy M.A., Janzen D., Weller S.J., Wahlberg N.;
RT "A molecular phylogenetic analysis of the vampire moths and their fruit-
RT piercing relatives (Lepidoptera: Erebidae: Calpinae).";
RL Mol. Phylogenet. Evol. 65:786-791(2012).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR EMBL; JN674995; AEZ54629.1; -; Genomic_DNA.
DR GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.
DR GO; GO:0006102; P:isocitrate metabolic process; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR004790; Isocitrate_DH_NADP.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11822:SF21; ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL; 1.
DR PANTHER; PTHR11822; NADP-SPECIFIC ISOCITRATE DEHYDROGENASE; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Glyoxylate bypass {ECO:0000256|ARBA:ARBA00022435};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Tricarboxylic acid cycle {ECO:0000256|ARBA:ARBA00022532}.
FT DOMAIN 1..216
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEZ54629.1"
FT NON_TER 216
FT /evidence="ECO:0000313|EMBL:AEZ54629.1"
SQ SEQUENCE 216 AA; 24640 MW; 83C10195C19E458B CRC64;
XMENRDKTDD QGTIDCAEAI KKYNVGIKCA TITPDENRVE EFKLKKMWKS PNGTIRNILG
GTVFREAIIC KNIPRLVTGW EKPIIIGRHA HADQYKATDF VVPGAGTLEL VFTPAFXEPI
RHVVNEYKGA GVALGMFNTD ASIIDFAHSS FKYALGRKYP LYLSTKNTIL KKYDGRFKDI
FQEIYDKEYK AQFEAAGIWY EHRLIDDMVA YSMKSE
//
