ID   H6VZE2_KLEPN            Unreviewed;       317 AA.
AC   H6VZE2;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Phosphoadenosine phosphosulfate reductase family protein {ECO:0000313|EMBL:AFB76165.1};
GN   ORFNames=R55_5 {ECO:0000313|EMBL:AFB76165.1};
OS   Klebsiella pneumoniae.
OG   Plasmid pR55 {ECO:0000313|EMBL:AFB76165.1}.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573 {ECO:0000313|EMBL:AFB76165.1};
RN   [1] {ECO:0000313|EMBL:AFB76165.1}
RP   NUCLEOTIDE SEQUENCE.
RC   PLASMID=pR55 {ECO:0000313|EMBL:AFB76165.1};
RX   PubMed=22773739; DOI=10.1093/jac/dks251;
RA   Doublet B., Boyd D., Douard G., Praud K., Cloeckaert A., Mulvey M.R.;
RT   "Complete nucleotide sequence of the multidrug resistance IncA/C plasmid
RT   pR55 from Klebsiella pneumoniae isolated in 1969.";
RL   J. Antimicrob. Chemother. 67:2354-2360(2012).
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DR   EMBL; JQ010984; AFB76165.1; -; Genomic_DNA.
DR   RefSeq; YP_005351875.1; NC_016976.1.
DR   AlphaFoldDB; H6VZE2; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR002500; PAPS_reduct.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR43196; SULFATE ADENYLYLTRANSFERASE SUBUNIT 2; 1.
DR   PANTHER; PTHR43196:SF1; SULFATE ADENYLYLTRANSFERASE SUBUNIT 2; 1.
DR   Pfam; PF01507; PAPS_reduct; 1.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
KW   Plasmid {ECO:0000313|EMBL:AFB76165.1}.
FT   DOMAIN          165..278
FT                   /note="Phosphoadenosine phosphosulphate reductase"
FT                   /evidence="ECO:0000259|Pfam:PF01507"
SQ   SEQUENCE   317 AA;  36839 MW;  6D9212131D54530E CRC64;
     MLRRENQGDL FDDQVVLPSL ESVLTGISSS QRCDDRTTYF SAPDVDLSLY DHIIVCLSGG
     KDSIAAYLRL VDMGVDKSKV EFWHHDVDGQ EGSSLMDWAF MRDYCRQLGE ELGIPMYFSW
     LEGGFEGEML KDNAYSHPHR VETPEGLLVL PRDHKRSKPG TRLRFPQQSP SLQTRWCSSA
     LKIDVGRRAL NNQERFKGKK ILFITGERRE ESANRSKYNQ LEAHACDRRY GKTARLVDAW
     RPVLHWTEEE VWEVIERHRI LAPVPYRLGW SRSSCMTCIY NSQRIWSTIR HYWPERAGKI
     AQYEQTFGVT VSRKKST
//