ID   H6W922_9HELO            Unreviewed;       249 AA.
AC   H6W922;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Oxaloacetate acetylhydrolase {ECO:0000313|EMBL:AEY84237.1};
DE   Flags: Fragment;
OS   Myriosclerotinia curreyana.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Myriosclerotinia.
OX   NCBI_TaxID=87228 {ECO:0000313|EMBL:AEY84237.1};
RN   [1] {ECO:0000313|EMBL:AEY84237.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=LMK759 {ECO:0000313|EMBL:AEY84237.1};
RX   PubMed=22253834; DOI=10.1371/journal.pone.0029943;
RA   Andrew M., Barua R., Short S.M., Kohn L.M.;
RT   "Evidence for a common toolbox based on necrotrophy in a fungal lineage
RT   spanning necrotrophs, biotrophs, endophytes, host generalists and
RT   specialists.";
RL   PLoS ONE 7:E29943-E29943(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate +
CC         succinate; Xref=Rhea:RHEA:16809, ChEBI:CHEBI:15361,
CC         ChEBI:CHEBI:30031, ChEBI:CHEBI:57429; EC=4.1.3.30;
CC         Evidence={ECO:0000256|ARBA:ARBA00001050};
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DR   EMBL; JQ035810; AEY84237.1; -; Genomic_DNA.
DR   AlphaFoldDB; H6W922; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00377; ICL_PEPM; 1.
DR   Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR   InterPro; IPR039556; ICL/PEPM.
DR   InterPro; IPR018523; Isocitrate_lyase_ph_CS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   PANTHER; PTHR42905; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR42905:SF2; PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN; 1.
DR   Pfam; PF13714; PEP_mutase; 1.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00161; ISOCITRATE_LYASE; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AEY84237.1};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AEY84237.1"
FT   NON_TER         249
FT                   /evidence="ECO:0000313|EMBL:AEY84237.1"
SQ   SEQUENCE   249 AA;  27021 MW;  5A970104B10F97B1 CRC64;
     QVGFPALYMT GAGTTASRLG MADLGIAHLS DMKDHAEMIA NLDPFGPPLI ADMDTGYGGP
     LIVDKAVKAY IRAGVAGFHI EDQIQNKRCG HLQGKKVVPE EEFYMRIRAA KGAKDAMNSD
     IVLIARTDAL QQLGYDECVK RLKVARDLGA DVGLLEGYTS KEMAAKTVRE FAPWPILLNM
     VENGSTPVIT TAEAQEMGFR IMIFSFAALA PAYLAIRETF LRLKRDGVVG TPKNLTPKAL
     FDVCGLKDS
//