ID H6WYF7_9CAUD Unreviewed; 864 AA.
AC H6WYF7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=DNA primase {ECO:0000313|EMBL:AFB84015.1};
OS Enterobacter phage Enc34.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Casjensviridae; Enchivirus; Enchivirus Enc34.
OX NCBI_TaxID=1150990 {ECO:0000313|EMBL:AFB84015.1, ECO:0000313|Proteomes:UP000008024};
RN [1] {ECO:0000313|EMBL:AFB84015.1, ECO:0000313|Proteomes:UP000008024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22997422; DOI=10.1128/JVI.01954-12;
RA Kazaks A., Dislers A., Lipowsky G., Nikolajeva V., Tars K.;
RT "Complete Genome Sequence of the Enterobacter cancerogenus Bacteriophage
RT Enc34.";
RL J. Virol. 86:11403-11404(2012).
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DR EMBL; JQ340774; AFB84015.1; -; Genomic_DNA.
DR RefSeq; YP_007007000.1; NC_019524.1.
DR GeneID; 14014076; -.
DR KEGG; vg:14014076; -.
DR OrthoDB; 5284at10239; -.
DR Proteomes; UP000008024; Genome.
DR GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR015330; DNA_primase/pol_bifunc_N.
DR InterPro; IPR045455; NrS-1_pol-like_helicase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014819; PriCT_2.
DR Pfam; PF19263; DUF5906; 1.
DR Pfam; PF08707; PriCT_2; 1.
DR Pfam; PF09250; Prim-Pol; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56747; Prim-pol domain; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008024}.
FT DOMAIN 14..161
FT /note="DNA primase/polymerase bifunctional N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09250"
FT DOMAIN 246..311
FT /note="Primase C-terminal 2"
FT /evidence="ECO:0000259|Pfam:PF08707"
FT DOMAIN 559..667
FT /note="NrS-1 polymerase-like helicase"
FT /evidence="ECO:0000259|Pfam:PF19263"
FT REGION 842..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..857
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 864 AA; 99083 MW; F90331D7605FD99F CRC64;
MNFWQRYGEI LRGNGYTIVP IYAPDAEKKG AGKRPIGEDW ETTVNTKEQI ERWAKRYTNN
GMGILTKHNP AVDIDVYDEK AVKHMSNWVE ANIGLAPCRI GRAPKKLFLY RAETPFSKVK
SGVWEDDFGQ RHAVEILADG QQFVAYGVHP ETKKEYFWTG VDSPENNIAD LDLEELSLDS
ARLITAEFDR YAELQGWTRV KRPFNGQESA EIGAADDDDW AATATITRWD GTYDELRELV
MKYPNPEDYE NWITLIAALQ ISCRDQDEAY AIAREWSEQA SNFDETEFDL KWEKGFDHKS
GSLVTIASII KVVKDIEYEE AAAAAVDFKE GFMSCENMVD WYSWADSFRK AQIFGALRKA
VVKVAAEKYR IFESLRMTAA EKKEYLGFDY GSREMPEWLK DFAFSKSNDA FIHKPTGDLI
TKGAFDTAFA QKCKFDDESF KPSVYASTVN KVPMVWDAMY YPEMHGDMPG SKWKQAEGLL
GPEYFYDRQG RMWLNTFDPE SIPEPAETLS KLDKKAIEII KDFFVVLFPD TKERTYVMDW
MAYVICNPTS RMNYSLLIRG AHGSGKTTLG VLMSKMLGRV NIGYVSNTVM NGRFTDWAEG
HILKVIEEIY DKGDRYSAIE RQKEFISNDE FMVEPKGRKA KEVINTSSKM MFTNHFNALP
LDENQRRYLV VSTQAENHLD MERVYGSVKE REKFFKDVYR AIENHSRAIK LWFTQWEFSP
SFNHRGHAPQ DTEAFSIMVD ASDDGVDGLI VQMLRDLNAP GVNRDVIFVP SLRDAFIDLA
GDVEMPKTNR LKNILMELGF KPGGVICYGG ITGRTYIRKR VRGAFDEKGK LNSKWVQQTL
KKHDSDVEKL NGTPHDPFDD EDEV
//
