ID H7C1X7_HUMAN Unreviewed; 215 AA.
AC H7C1X7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Kalirin RhoGEF kinase {ECO:0000313|Ensembl:ENSP00000402950.2};
DE Flags: Fragment;
GN Name=KALRN {ECO:0000313|Ensembl:ENSP00000402950.2};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000402950.2, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000402950.2, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000402950.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC022336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC069233; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC080008; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC112129; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC117381; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC117401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF457679; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H7C1X7; -.
DR SMR; H7C1X7; -.
DR MassIVE; H7C1X7; -.
DR MaxQB; H7C1X7; -.
DR PeptideAtlas; H7C1X7; -.
DR ProteomicsDB; 44794; -.
DR Antibodypedia; 2142; 205 antibodies from 34 providers.
DR Ensembl; ENST00000439170.2; ENSP00000402950.2; ENSG00000160145.16.
DR UCSC; uc062neq.1; human.
DR HGNC; HGNC:4814; KALRN.
DR VEuPathDB; HostDB:ENSG00000160145; -.
DR GeneTree; ENSGT00940000155248; -.
DR HOGENOM; CLU_1285908_0_0_1; -.
DR ChiTaRS; KALRN; human.
DR Proteomes; UP000005640; Chromosome 3.
DR Bgee; ENSG00000160145; Expressed in secondary oocyte and 167 other cell types or tissues.
DR ExpressionAtlas; H7C1X7; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00176; SPEC; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR46607; SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46607:SF1; SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00435; Spectrin; 1.
DR SMART; SM00150; SPEC; 2.
DR SUPFAM; SSF46966; Spectrin repeat; 2.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:H7C1X7,
KW ECO:0007829|PeptideAtlas:H7C1X7};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000402950.2"
SQ SEQUENCE 215 AA; 24838 MW; 8CCE13D77A1290BE CRC64;
WQHRKVRLHQ RLQLCVFQQD VQQVLDWIEN HGEAFLSKHT GVGKSLHRAR ALQKRHDDFE
EVAQNTYTNA DKLLEAAEQL AQTGECDPEE IYKAARHLEV RIQDFVRRVE QRKLLLDMSV
SFHTHTKELW TWMEDLQKEM LEDVCADSVD AVQELIKQFQ QQQTATLDAT LNVIKEGEDL
IQQLRSAPPS LGEPSEARSA WAELSSGKCL GLDVR
//
