ID H7C695_CORGT Unreviewed; 331 AA.
AC H7C695;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU362124};
GN Name=sigB {ECO:0000313|EMBL:CAA89988.1};
GN ORFNames=BBD29_09100 {ECO:0000313|EMBL:ANU33900.1};
OS Corynebacterium glutamicum (Brevibacterium saccharolyticum).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1718 {ECO:0000313|EMBL:CAA89988.1};
RN [1] {ECO:0000313|EMBL:CAA89988.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 13869 {ECO:0000313|EMBL:CAA89988.1};
RX PubMed=8550480;
RA Oguiza J.A., Marcos A.T., Malumbres M., Martin J.F.;
RT "Multiple sigma factor genes in Brevibacterium lactofermentum:
RT characterization of sigA and sigB.";
RL J. Bacteriol. 178:550-553(1996).
RN [2] {ECO:0000313|Proteomes:UP000092697}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13869 {ECO:0000313|Proteomes:UP000092697};
RA Chen X., Yang J., Jiang Y., Yang S., Zhang Y.;
RT "Genome sequence of Corynebacterium glutamicum ATCC 13869.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ANU33900.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 13869 {ECO:0000313|EMBL:ANU33900.1};
RX PubMed=28198668;
RA Yang J., Yang S.;
RT "Comparative analysis of Corynebacterium glutamicum genomes: a new
RT perspective for the industrial production of amino acids.";
RL BMC Genomics 18:940-940(2017).
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. {ECO:0000256|RuleBase:RU362124}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family.
CC {ECO:0000256|RuleBase:RU362124}.
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DR EMBL; CP016335; ANU33900.1; -; Genomic_DNA.
DR EMBL; Z49824; CAA89988.1; -; Genomic_DNA.
DR RefSeq; WP_011014752.1; NZ_LOQS01000008.1.
DR AlphaFoldDB; H7C695; -.
DR KEGG; cgj:AR0_09040; -.
DR KEGG; cgq:CGLAR1_08890; -.
DR PATRIC; fig|1718.43.peg.1845; -.
DR OMA; MDAPFVQ; -.
DR Proteomes; UP000092697; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.10.601.10; RNA Polymerase Primary Sigma Factor; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30603; RNA POLYMERASE SIGMA FACTOR RPO; 1.
DR PANTHER; PTHR30603:SF47; RNA POLYMERASE SIGMA FACTOR SIGF, CHLOROPLASTIC; 1.
DR Pfam; PF00140; Sigma70_r1_2; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR PROSITE; PS00715; SIGMA70_1; 1.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362124};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU362124}.
FT DOMAIN 122..135
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00715"
FT DOMAIN 291..317
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00716"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 331 AA; 37556 MW; 4F717F3BB395EEC1 CRC64;
MTAPSTQDLA TTEREVDPGS RRGQTNDNPS QDLVRVYLNG IGKTALLTAE DEVELAQTIE
VGLYAEHLLK NSEEPLTRAM KRDLKVLAKD GKKARSHLLE ANLRLVVSLA KRYTGRGMPL
LDLIQEGNLG LIRAMEKFDY SKGFKFSTYA TWWIRQAITR GMADQSRTIR LPVHLVEQVN
KLSRIKRELY QHLGREATNE ELAEESGIEE SKIEMLLRQS RDPVSLDMPV GADEEAPLGD
FIEDSEATDA ESAVVASMRH SDIRAVLNTL EPREQDVIRL RYGLDDGVPR TLDQIGRRFG
LSRERVRQIE REVMSKLRDG ERASRLREYA Q
//
