ID H8G4C7_9PSEU Unreviewed; 322 AA.
AC H8G4C7;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:EHY87098.1};
GN ORFNames=SacazDRAFT_00110 {ECO:0000313|EMBL:EHY87098.1};
OS Saccharomonospora azurea NA-128.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharomonospora.
OX NCBI_TaxID=882081 {ECO:0000313|EMBL:EHY87098.1};
RN [1] {ECO:0000313|EMBL:EHY87098.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA-128 {ECO:0000313|EMBL:EHY87098.1};
RX PubMed=22768365; DOI=10.4056/sigs.2635833;
RA Klenk H.P., Held B., Lucas S., Lapidus A., Copeland A., Hammon N.,
RA Pitluck S., Goodwin L.A., Han C., Tapia R., Brambilla E.M., Potter G.,
RA Land M., Ivanova N., Rohde M., Goker M., Detter J.C., Kyrpides N.C.,
RA Woyke T.;
RT "Genome sequence of the soil bacterium Saccharomonospora azurea type strain
RT (NA-128(T)).";
RL Stand. Genomic Sci. 6:220-229(2012).
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DR EMBL; CM001466; EHY87098.1; -; Genomic_DNA.
DR RefSeq; WP_005437618.1; NZ_CM001466.1.
DR AlphaFoldDB; H8G4C7; -.
DR HOGENOM; CLU_009834_0_1_11; -.
DR OrthoDB; 9771883at2; -.
DR Proteomes; UP000004705; Chromosome.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF1; LAMBDA-CRYSTALLIN HOMOLOG; 1.
DR Pfam; PF00725; 3HCDH; 1.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
FT DOMAIN 14..187
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 193..261
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 322 AA; 34399 MW; B779650473FD4C70 CRC64;
MTSAATWSPQ EVETVACVGA GVIGGGWAAH FLARGYTVRA WDPGDGAAER LSRLVEAAWP
ALTELGLADG ASPDNLTVVP TLAEAVDGAG FVQESAPEAL DLKRRLLADI DAVTAPGVVI
ASSTSGFAMT DMQVDAATPE RLVVGHPFNP PYLIPLVEVV GGERTERWAV DWASDFYRHV
GKSVITMDRE LPGFIANRLQ EALWREALHM VANGEATPEQ IDTAITDGPG LRWPVQGPCL
TFHLAGGEGG MAHMLDHFGP ALKEPWTRLD APELTSRLRD DMVAGCESEA DGRTFLDLVS
ERDRGVIAVQ RALRALKDGG DE
//
