ID   H8G542_9PSEU            Unreviewed;      1732 AA.
AC   H8G542;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   16-MAY-2012, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=IstB-like ATP binding protein {ECO:0000313|EMBL:EHY91221.1};
GN   ORFNames=SacazDRAFT_04381 {ECO:0000313|EMBL:EHY91221.1};
OS   Saccharomonospora azurea NA-128.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharomonospora.
OX   NCBI_TaxID=882081 {ECO:0000313|EMBL:EHY91221.1};
RN   [1] {ECO:0000313|EMBL:EHY91221.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA-128 {ECO:0000313|EMBL:EHY91221.1};
RX   PubMed=22768365; DOI=10.4056/sigs.2635833;
RA   Klenk H.P., Held B., Lucas S., Lapidus A., Copeland A., Hammon N.,
RA   Pitluck S., Goodwin L.A., Han C., Tapia R., Brambilla E.M., Potter G.,
RA   Land M., Ivanova N., Rohde M., Goker M., Detter J.C., Kyrpides N.C.,
RA   Woyke T.;
RT   "Genome sequence of the soil bacterium Saccharomonospora azurea type strain
RT   (NA-128(T)).";
RL   Stand. Genomic Sci. 6:220-229(2012).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM001466; EHY91221.1; -; Genomic_DNA.
DR   HOGENOM; CLU_000738_1_0_11; -.
DR   OrthoDB; 3197455at2; -.
DR   Proteomes; UP000004705; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   Gene3D; 3.40.960.10; VSR Endonuclease; 1.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011335; Restrct_endonuc-II-like.
DR   InterPro; IPR049468; Restrct_endonuc-II-like_dom.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR43788:SF8; HELICASE WITH ZINC FINGER 2; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF18741; MTES_1575; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   SUPFAM; SSF52980; Restriction endonuclease-like; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          362..523
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          1131..1318
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   DOMAIN          1372..1464
FT                   /note="Restriction endonuclease type II-like"
FT                   /evidence="ECO:0000259|Pfam:PF18741"
FT   REGION          51..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1485..1564
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          469..496
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1537..1559
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1732 AA;  193800 MW;  C67ED4DE8C62C389 CRC64;
     MVERARNLFE FLQRAQELKT TAPRTTDRYQ REGEVLWFAD FPEHPAVQHA NGLTSPASDS
     PLLTVDRIPR RTPPQPGTGL ERWLLGRWDD PDRAPELRES LTIAVRDGAE GDQVTRQVRV
     TEYPHIREAY ESWRAEWAAW AEEELRDRPA RDFYNLLFSL FLKVKDSPEE VELVAGTACL
     SWRPEGHPEV SRHVFTSPLI VEFDDATGRL AVVVGDTPEA FKTELDMLDP GLIKATETVN
     EVRAAVRALH VHPLDREELG LFGRRLVHAL DADGEYRDED RPAAATEDAT VTFAPALILR
     KRSQRGLVEV FQTLTGQLAG AETVPDGILP LLDPDQVPAV EPTTTGGALV TVDDESFLPM
     PVNERQREII ERVDRQAQVL VQGPPGTGKT HTAAALISHL LAQGKRVLVT AQTDRALREV
     RDKLPDQIKP LSVAVVGTSR DDMADLKVAV QEIAAAAHDH DTKRNAREIE GCLAEIDRLR
     RERAEVYRDL LAARESEVRQ HDRGDYRGTL ADIAKQIEDQ EREYGWVLEH VPEGMADEPP
     LTGQEVLEWR QHLLDGELAA DEPEARQQLV ALDALPSPAR FATFVTAERG AEARRREREE
     LRHHPAFPAI LRLDASQRDE LRKRLGRIAD EQTVLAGGPE QWIPAALADV CAGREAAWRA
     QAEQLAALIE QTAQHVQRLG ALTEVELPDD DAARMVALAR EVLRYLEEGH RVKTAADGTP
     KVGRLAPKVL KQAQPLFDSV KVDGLPPTNT GQLLAVVTWF EASKMLAALD RTWPGRGDSK
     TDPLHVRLQW HRTELGQLWR VLRLAEELRA EERRLAELGI PLPDWSDATA LNTCQALCDT
     VEVEKAWAAA QEPLAVLTTT LAEIVGDDVA PVVRRLRAAV DERDADEYGV AHARLARLWA
     IREQASRRDD LGRRLASAVP GLFRAVAAAP EDATWTGRLE RFESAWAWAA TRSWVRTQES
     LDVNALQQRT GRIDDRIRRQ VETLAARRAW DYAASPERLN GSARADLTQY AQLVQRAGKL
     TGKYAAVQRA GIRQAMERCR PSVPAWIMPI YRIAEQLRIT PDMFDVVIVD EASQAGMEAT
     FLQYLAPKIV VIGDDKQVSP SAVGVDQQQL RDLAGQYLAG DRYRESWQDP QRSLFDEAKM
     RYGGVITLTE HRRCVPEIIG FSNRIAYEPD NIRLIPVRQY GADRLDPVKA VYLPDGYQRG
     TTNKINPVEA EAIVDQIEKC LADPAYENRT FGVISLLGPA QARYIESKLL DRIGKEQWTA
     RDLRCGDASD FQGSERDVVF LSMVAVPEEG RRLAALTADR YVQRYNVAVS RAKDQVWLYH
     SVERQALNNK EDMRFQLLDY CYGVIERGRS SDQRASDLVP EDERVPPFDS LFEQRVHNRI
     VTRGYTVVPQ YESAGYRIDL VVVGGGDRLA VECDGDRWHG PEAFERDLAR QRELERCGWS
     FFRVRESLFY VDPAGALDGL WKMLDDRDIR PVGELREPPC RAELESTTIE NPELAGTFEQ
     TGGESPPETK EGKDGTPESA WLGAHLGAAT TTAENSDDTR HASEAVEHGE AEEVRTPEPL
     GDETVPYEEF SGVVPPVDTG LRADIIEGLR SIVAVEGPVL GERLQAVYVK ASGKQRVGKQ
     IAKKLNSVIS DAVRRGVLAC DNPLQVSGVK YRTYRLPGQQ VRIRERGPRK LDQVPPDELA
     AMMRAVTHER GSHDEEEVLR GTAERLGVGR LTEQVRTHLL SVLPLARKGV EQ
//