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Database: UniProt
Entry: H8GFW9_METAL
LinkDB: H8GFW9_METAL
Original site: H8GFW9_METAL 
ID   H8GFW9_METAL            Unreviewed;       239 AA.
AC   H8GFW9;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   16-MAY-2012, sequence version 1.
DT   05-JUL-2017, entry version 30.
DE   RecName: Full=Flagellar brake protein YcgR {ECO:0000256|HAMAP-Rule:MF_01457};
DE   AltName: Full=Cyclic di-GMP binding protein YcgR {ECO:0000256|HAMAP-Rule:MF_01457};
GN   Name=ycgR {ECO:0000256|HAMAP-Rule:MF_01457};
GN   ORFNames=Metal_0896 {ECO:0000313|EMBL:EIC28720.1};
OS   Methylomicrobium album BG8.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Methylococcales;
OC   Methylococcaceae; Methylomicrobium.
OX   NCBI_TaxID=686340 {ECO:0000313|EMBL:EIC28720.1, ECO:0000313|Proteomes:UP000005090};
RN   [1] {ECO:0000313|EMBL:EIC28720.1, ECO:0000313|Proteomes:UP000005090}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BG8 {ECO:0000313|EMBL:EIC28720.1,
RC   ECO:0000313|Proteomes:UP000005090};
RX   PubMed=23580712;
RA   Kits K.D., Kalyuzhnaya M.G., Klotz M.G., Jetten M.S.,
RA   Op den Camp H.J., Vuilleumier S., Bringel F., Dispirito A.A.,
RA   Murrell J.C., Bruce D., Cheng J.F., Copeland A., Goodwin L.,
RA   Hauser L., Lajus A., Land M.L., Lapidus A., Lucas S., Medigue C.,
RA   Pitluck S., Woyke T., Zeytun A., Stein L.Y.;
RT   "Genome Sequence of the Obligate Gammaproteobacterial Methanotroph
RT   Methylomicrobium album Strain BG8.";
RL   Genome Announc. 1:E0017013-E0017013(2013).
CC   -!- FUNCTION: Acts as a flagellar brake, regulating swimming and
CC       swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-
CC       dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing
CC       levels of c-di-GMP lead to decreased motility. {ECO:0000256|HAMAP-
CC       Rule:MF_01457}.
CC   -!- SUBUNIT: Monomer. Interacts with the flagellar basal bodies.
CC       {ECO:0000256|HAMAP-Rule:MF_01457}.
CC   -!- SUBCELLULAR LOCATION: Bacterial flagellum basal body
CC       {ECO:0000256|HAMAP-Rule:MF_01457}.
CC   -!- SIMILARITY: Belongs to the YcgR family. {ECO:0000256|HAMAP-
CC       Rule:MF_01457}.
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DR   EMBL; CM001475; EIC28720.1; -; Genomic_DNA.
DR   RefSeq; WP_005369994.1; NZ_CM001475.1.
DR   EnsemblBacteria; EIC28720; EIC28720; Metal_0896.
DR   OrthoDB; POG091H0NAE; -.
DR   Proteomes; UP000005090; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0035438; F:cyclic-di-GMP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-HAMAP.
DR   GO; GO:0071945; P:regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed; IEA:UniProtKB-HAMAP.
DR   Gene3D; 2.30.110.10; -; 1.
DR   HAMAP; MF_01457; YcgR; 1.
DR   InterPro; IPR009875; PilZ_domain.
DR   InterPro; IPR012349; Split_barrel_FMN-bd.
DR   InterPro; IPR023787; T3SS_YcgR.
DR   InterPro; IPR009926; T3SS_YcgR_N.
DR   Pfam; PF07238; PilZ; 1.
DR   Pfam; PF07317; YcgR; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum {ECO:0000256|HAMAP-Rule:MF_01457};
KW   c-di-GMP {ECO:0000256|HAMAP-Rule:MF_01457};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005090};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01457};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005090};
KW   Transferase {ECO:0000313|EMBL:EIC28720.1}.
FT   DOMAIN        7    110       T3SS_YcgR_N. {ECO:0000259|Pfam:PF07317}.
FT   DOMAIN      114    226       PilZ. {ECO:0000259|Pfam:PF07238}.
SQ   SEQUENCE   239 AA;  27502 MW;  CA8DDD485A9A0F58 CRC64;
     MFNDTDYMVH NKSQILNHLT SLFKKKCLIL LSFDKNGTFV TTLAAIEPQK DLLLFDCAPS
     EHLNSQVLSA SQVEFNSNFS GIKVHFQGKN IRKTHFDGET VFSMPIPKSI EWVQRRQFYR
     IRLPLLRSTL VKLFVDDQFL ADMPLYDISI SGFSLINDIS GLSHFFEIGR KFSGCRLVLE
     NAFNQEIEFQ VVNVVRLNPN QHDSAQKIGC RFIGLRPAAE SGIQLYMQYQ ERKNLSKKT
//
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