ID H8GGX3_METAL Unreviewed; 378 AA.
AC H8GGX3;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:EIC31248.1};
GN ORFNames=Metal_3601 {ECO:0000313|EMBL:EIC31248.1};
OS Methylomicrobium album BG8.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomicrobium.
OX NCBI_TaxID=686340 {ECO:0000313|EMBL:EIC31248.1, ECO:0000313|Proteomes:UP000005090};
RN [1] {ECO:0000313|EMBL:EIC31248.1, ECO:0000313|Proteomes:UP000005090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BG8 {ECO:0000313|EMBL:EIC31248.1,
RC ECO:0000313|Proteomes:UP000005090};
RX PubMed=23580712;
RA Kits K.D., Kalyuzhnaya M.G., Klotz M.G., Jetten M.S., Op den Camp H.J.,
RA Vuilleumier S., Bringel F., Dispirito A.A., Murrell J.C., Bruce D.,
RA Cheng J.F., Copeland A., Goodwin L., Hauser L., Lajus A., Land M.L.,
RA Lapidus A., Lucas S., Medigue C., Pitluck S., Woyke T., Zeytun A.,
RA Stein L.Y.;
RT "Genome Sequence of the Obligate Gammaproteobacterial Methanotroph
RT Methylomicrobium album Strain BG8.";
RL Genome Announc. 1:E0017013-E0017013(2013).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CM001475; EIC31248.1; -; Genomic_DNA.
DR RefSeq; WP_005374487.1; NZ_CM001475.1.
DR AlphaFoldDB; H8GGX3; -.
DR STRING; 686340.Metal_3601; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_1_6; -.
DR Proteomes; UP000005090; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005090}.
FT DOMAIN 56..287
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 378 AA; 40803 MW; C4098B84122A4CF9 CRC64;
MRKKTLTTLA ILAIAFALAV YYKRPEPVEV KIVSIEEGEV RSTVSNTRVG TVKACRRAYL
APAAGGQVAQ LNVKEGDKVR KNELLMEVWN HDLKAQLALQ EAQIRANHAA AEQACQLKGG
AIREAERISR LQKYNHIVSE EQVDTKVTNA KAQSAACLSA KAAVDVSQAS RDAAKAAIER
TYVEAPFDGT VAEINVELGE YVTPSPPGIP TLPAIDLLDV SCLYVSAPID EVDAPQIKTG
MTAYVSLDAF PGRRSLGTVS RIAPYVLEKE KQARTVEVEV KLTDPKDLQE LLPGYSADIE
VLLAGKPKAL RVPAEAVIEN HKVLLLNENG VLVERTFKPG LANWNYVEVL EGLKPGDKVV
LSVGQEGVTA GARAQAKP
//
