ID   H8GIT3_METAL            Unreviewed;      1304 AA.
AC   H8GIT3;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   16-MAY-2012, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:EIC30273.1};
GN   ORFNames=Metal_2557 {ECO:0000313|EMBL:EIC30273.1};
OS   Methylomicrobium album BG8.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC   Methylococcaceae; Methylomicrobium.
OX   NCBI_TaxID=686340 {ECO:0000313|EMBL:EIC30273.1, ECO:0000313|Proteomes:UP000005090};
RN   [1] {ECO:0000313|EMBL:EIC30273.1, ECO:0000313|Proteomes:UP000005090}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BG8 {ECO:0000313|EMBL:EIC30273.1,
RC   ECO:0000313|Proteomes:UP000005090};
RX   PubMed=23580712;
RA   Kits K.D., Kalyuzhnaya M.G., Klotz M.G., Jetten M.S., Op den Camp H.J.,
RA   Vuilleumier S., Bringel F., Dispirito A.A., Murrell J.C., Bruce D.,
RA   Cheng J.F., Copeland A., Goodwin L., Hauser L., Lajus A., Land M.L.,
RA   Lapidus A., Lucas S., Medigue C., Pitluck S., Woyke T., Zeytun A.,
RA   Stein L.Y.;
RT   "Genome Sequence of the Obligate Gammaproteobacterial Methanotroph
RT   Methylomicrobium album Strain BG8.";
RL   Genome Announc. 1:E0017013-E0017013(2013).
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DR   EMBL; CM001475; EIC30273.1; -; Genomic_DNA.
DR   RefSeq; WP_005372837.1; NZ_CM001475.1.
DR   STRING; 686340.Metal_2557; -.
DR   eggNOG; COG1643; Bacteria.
DR   HOGENOM; CLU_001832_3_3_6; -.
DR   Proteomes; UP000005090; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   CDD; cd17989; DEXHc_HrpA; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:EIC30273.1};
KW   Hydrolase {ECO:0000313|EMBL:EIC30273.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005090}.
FT   DOMAIN          85..248
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          289..453
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1304 AA;  149677 MW;  F42C508FC2593B1D CRC64;
     MSLSETLKQL SRQLPQCLNQ DRHGFKRQLD RLRNEYQKGK NPIAQVAALQ AKIGQSAERR
     RQRLASVPVL NFPDLPVTGK KDEIAELIRN NQVVIVCGET GSGKTTQLPK ICLSIGLGSG
     GFIGHTQPRR IAARTVADRI AEELGEPLGK SVGFKVRFTD KTHADSLVKL MTDGILLAET
     QNDPYLNQYD TIIIDEAHER SLNIDFLLGY MKWLLPKRPD LKLIITSATI DPERFSRHFF
     DAPIIEVSGR TYPVEIRYRP VEETEQDEEG KKTANDETSD NLQQAILEAV DELVRDVRGD
     ILIFMSGERE IKETTESLKK HHPSKYEILP LYAKLSTSEQ ERVFKPKGGK IRIVLATNVA
     ETSLTVPGIR AVIDTGHARI SRYSHRSKIQ RLPIERISQS SANQRAGRCG RVAEGICIRL
     YSAEDYQARP EFTEPEILRT NLSAVILQMT ALNLGDIEDF PFIEPPEDKM IRDGKTVLQE
     VNALDKQGKL TEIGKQLVKF PTDPRLARML IAAEKQHALH EVAIIVSALS IQDPREKPAD
     KLAQAEAKQA RFRHEDSDFL TLLNLWNDFE EQKKHLSNNK LRKYCSDHFL SYIRMREWVD
     IHAQIMQVIK GDLNLKINTV PASYAEIHRA LLPGLLSNIG FRHEQYEYLG ARGLKFFIFP
     GSGQYKARPK WIMAAEQVET SKIYARTVAK VEPEWIEECA EYLVKRNYYD PHWEKKAARS
     AVHERTLLFG LTLQAGRKVP YEHVDPKAAR EIFIRSALVD HDYHSNAPFY LANRTLLEEV
     GYIQHKGRRV DLIEDEEWLY RFYDEKIPAE VVNGVTFDQW RKKVERDNPK CLFLTREDLT
     REQDHAVNEW DYPDSKKVGN LTIRLQYRFE PGHDEDGVTA IIPVHQLNQV SQTPFDWLVP
     GLLEEKCVAL VKSLPKPIRK HFVPVPETVK KCLEIEPDFK GSLYEWLGNR LRKLTGEAIP
     LNAWNPESLP EHLKMNFRVV DDRGKLLDYG RDLKKLQAKH GVVAGDSFDQ LAADELNYTG
     CIQWAFGDLP DTRQFMQRGQ SFIGYPAIVD EGDAVGVRLF DTERKAAQQH QAGLMRLYQL
     QLRKECTYIQ KNAPQSAAAE LAYQRLPKHP IIQYQRSGSY KEDLLFCILS HVFIEGRTIR
     NKEAFERNLQ AAKPNLIAAA NDIGKIVPDI MLQYADIKAR TGKLNPNDSL AKDVNQQLDL
     LIYAGFIRHT PYDQLKAIPR YLKAVLYRLD KFVNDPQKNQ EIQRYAIRFW QDVEKKSKKE
     TVIPEQDPFR WALEEFRVSL YAQQLKTAFP VSAKRLEKAW DERG
//