ID H8IQU7_MYCIA Unreviewed; 506 AA.
AC H8IQU7;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN OrderedLocusNames=OCU_42840 {ECO:0000313|EMBL:AFC45503.1};
OS Mycobacterium intracellulare (strain ATCC 13950 / DSM 43223 / JCM 6384 /
OS NCTC 13025 / 3600).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=487521 {ECO:0000313|EMBL:AFC45503.1, ECO:0000313|Proteomes:UP000008004};
RN [1] {ECO:0000313|EMBL:AFC45503.1, ECO:0000313|Proteomes:UP000008004}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13950 / DSM 43223 / JCM 6384 / NCTC 13025 / 3600
RC {ECO:0000313|Proteomes:UP000008004};
RX PubMed=22535933; DOI=10.1128/JB.00295-12;
RA Kim B.J., Choi B.S., Lim J.S., Choi I.Y., Lee J.H., Chun J., Kook Y.H.,
RA Kim B.J.;
RT "Complete genome sequence of Mycobacterium intracellulare strain ATCC
RT 13950T.";
RL J. Bacteriol. 194:2750-2750(2012).
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DR EMBL; CP003322; AFC45503.1; -; Genomic_DNA.
DR RefSeq; WP_014381093.1; NZ_CP076382.1.
DR AlphaFoldDB; H8IQU7; -.
DR GeneID; 77300239; -.
DR KEGG; mia:OCU_42840; -.
DR PATRIC; fig|487521.10.peg.4292; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_1_10_11; -.
DR Proteomes; UP000008004; Chromosome.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:InterPro.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF4; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 17..486
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 506 AA; 54083 MW; 7E343CF99B678648 CRC64;
MTTQIPHFID GRRTAGQSGR TADVFDPSTG SVQAQVPMAG QADIDAAVAS ALEAQKGWAA
TNPQRRARVM MRFIELVNKH NDELAELLSR EHGKTLADAK GDIQRGIEVI EFAIGIPHLL
KGEYSEGAGP GIDVYSLRQP LGVVAGITPF NFPAMIPLWK AGPALACGNA FVLKPSERDP
SVPVRLAELF VEAGLPPGVF QVVHGDKEAV DAILNHPDIQ AVGFVGSSDI AQYIYAGAAA
TGKRSQCFGG AKNHMIVMPD ADLDQAVDAL IGAGYGSAGE RCMAISVAVP VGEQTADRLR
ARLIERINNL RVGHSLDPKA DYGPLVTEAA VARVRDYIGQ GVDAGAELVI DGRERASDDL
TFGDANLEGG FFIGPTLFDH VTPDMSIYTD EIFGPVLCIV RAHDYEEALR LPSEHEYGNG
VAIFTRDGDA ARDFVSRVQV GMVGVNVPIP VPVAYHTFGG WKRSGFGDLN QHGPSSILFY
TKTKTVTSRW PSGIKDGAEF VIPTMD
//
