ID H8K2X2_RICAG Unreviewed; 299 AA.
AC H8K2X2;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Hemolysin C {ECO:0000313|EMBL:AFC70240.1};
GN OrderedLocusNames=MCE_07300 {ECO:0000313|EMBL:AFC70240.1};
OS Rickettsia amblyommatis (strain GAT-30V) (Rickettsia amblyommii).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX NCBI_TaxID=1105111 {ECO:0000313|EMBL:AFC70240.1, ECO:0000313|Proteomes:UP000008005};
RN [1] {ECO:0000313|Proteomes:UP000008005}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAT-30V {ECO:0000313|Proteomes:UP000008005};
RA Johnson S.L., Munk A.C., Han S., Bruce D.C., Dasch G.A.;
RT "Complete genome sequence of Candidatus Rickettsia amblyommii strain GAT-
RT 30V.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFC70240.1, ECO:0000313|Proteomes:UP000008005}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAT-30V {ECO:0000313|EMBL:AFC70240.1,
RC ECO:0000313|Proteomes:UP000008005};
RX PubMed=27638476; DOI=10.1099/ijsem.0.001502;
RA Karpathy S.E., Slater K.S., Goldsmith C.S., Nicholson W.L., Paddock C.D.;
RT "Rickettsia amblyommatis sp. nov., a spotted fever group Rickettsia
RT associated with multiple species of Amblyomma ticks in North, Central and
RT South America.";
RL Int. J. Syst. Evol. Microbiol. 66:5236-5243(2016).
CC -!- SIMILARITY: Belongs to the UPF0053 family. Hemolysin C subfamily.
CC {ECO:0000256|ARBA:ARBA00006446}.
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DR EMBL; CP003334; AFC70240.1; -; Genomic_DNA.
DR RefSeq; WP_014392740.1; NC_017028.1.
DR AlphaFoldDB; H8K2X2; -.
DR STRING; 1105111.MCE_07300; -.
DR KEGG; ram:MCE_07300; -.
DR HOGENOM; CLU_015237_3_1_5; -.
DR Proteomes; UP000008005; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF27; MAGNESIUM AND COBALT EFFLUX PROTEIN CORC; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 80..142
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 145..202
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 299 AA; 33892 MW; F4688A245EBB50F1 CRC64;
MLKSSNKEDS SKKNQNNKLI FTVRKLFSPI KNFFRKTKTP DNFFGVIKRL KINSQKMTLD
ERNILANLLE LEDKTIEDIM VPRSDIAAIK LTTNLEELSE SIKLEVPHTR TLIYDGTLDN
VVGFIHIKDL FKALATKQNG RLKKLIRKHI IAAPSMKLLD LLAKMRRERT HIAIVVDEYG
GTDGLVTIED LIEEIVGRID DEHDQQLDSD NFKVINNSTI ISNARVEVEV LEEIIGEKLQ
NDDDEFDTIG GLVLTRVSSV PAIGTRIDIS ENIEIEVTDA TPRSLKQVKI RLKNGLHGK
//
