ID H8KP80_SOLCM Unreviewed; 593 AA.
AC H8KP80;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:AFD05717.1};
GN OrderedLocusNames=Solca_0587 {ECO:0000313|EMBL:AFD05717.1};
OS Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB
OS 12057 / USAM 9D) (Flexibacter canadensis).
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Solitalea.
OX NCBI_TaxID=929556 {ECO:0000313|EMBL:AFD05717.1, ECO:0000313|Proteomes:UP000007590};
RN [1] {ECO:0000313|Proteomes:UP000007590}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D
RC {ECO:0000313|Proteomes:UP000007590};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Lu M.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Spring S., Schroeder M., Kopitz M., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of Solitalea canadensis DSM 3403.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; CP003349; AFD05717.1; -; Genomic_DNA.
DR RefSeq; WP_014678945.1; NC_017770.1.
DR AlphaFoldDB; H8KP80; -.
DR STRING; 929556.Solca_0587; -.
DR KEGG; scn:Solca_0587; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_011781_2_1_10; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000007590; Chromosome.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 2.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:AFD05717.1};
KW Hydrolase {ECO:0000313|EMBL:AFD05717.1};
KW Protease {ECO:0000313|EMBL:AFD05717.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007590}.
FT DOMAIN 7..125
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 310..524
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 533..593
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 593 AA; 66318 MW; 7545F758D8534A0B CRC64;
MTYKEKLSAI RSQMEQNGVD AYIIPSSDPH ISEYLPDHYK CMEWTSGFSG SAGTLVITAD
FAGLWTDARY FVQAVDQLKD TGFELVKLKI QHTPEYIEWL AEKLQKGATV AFDGKLISAE
LVKIMKVGFN RFGFNLNTKA DFITPIWENR PAFLNNPVFL LPEDITGEST ESKIARLRAD
MKKQQVDFHL ISSMDDIAWL LNVRGSDVDC NPLVLSHVLV SQNELVWFVN DTRITPADKA
ALAKSGVDIN CYMQFATSVS ALPAGNSVLI DPKKLCQEVM EAIPSGVSIV EGMNPTTMFK
SIKNKTEQQH IRQTMVNDGV AMVKFLKWLE DNIGKTYIDE LSASAKLYEF RSAQPGFVGE
SFGTISAYKG HAALPHYKST PESNVELKPE GIYLVDSGGQ YRTGTTDITR TISLGNSTAE
EKKDYTLVLK GMIDLSMARF PEGTKGYQLD AFSRRWLWQE GYNFGHGTGH GVGFFLNVHE
GPQNISVSGA INIAFQPGML NSNEPGIYRP EKHGIRIENL VICQEDVKTE FGQFLNFETV
TICPIATDLI DAALLNEAQR SWFNDYHKFV FDKLSPLLNV DEQAWLKEKT KAI
//
