ID H8LQ94_RICSL Unreviewed; 1582 AA.
AC H8LQ94;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=NAD-specific glutamate dehydrogenase {ECO:0000313|EMBL:AFD20171.1};
GN ORFNames=MC3_06545 {ECO:0000313|EMBL:AFD20171.1};
OS Rickettsia slovaca str. D-CWPP.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX NCBI_TaxID=1105109 {ECO:0000313|EMBL:AFD20171.1, ECO:0000313|Proteomes:UP000007592};
RN [1] {ECO:0000313|EMBL:AFD20171.1, ECO:0000313|Proteomes:UP000007592}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D-CWPP (RSB) {ECO:0000313|Proteomes:UP000007592};
RA Johnson S.L., Munk A.C., Han S., Bruce D.C., Dasch G.A.;
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003375; AFD20171.1; -; Genomic_DNA.
DR RefSeq; WP_014273782.1; NC_017065.1.
DR KEGG; rsw:MC3_06545; -.
DR PATRIC; fig|1105109.3.peg.1380; -.
DR HOGENOM; CLU_003404_1_1_5; -.
DR Proteomes; UP000007592; Chromosome.
DR GO; GO:0004352; F:glutamate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0019551; P:glutamate catabolic process to 2-oxoglutarate; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR048381; GDH_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR028971; NAD-GDH_cat.
DR InterPro; IPR049062; NAD_Glu_DH_ACT2.
DR InterPro; IPR049064; NAD_Glu_DH_ACT3.
DR InterPro; IPR007780; NAD_Glu_DH_bac.
DR InterPro; IPR049059; NAD_Glu_DH_HM1.
DR InterPro; IPR049056; NAD_Glu_DH_HM3.
DR InterPro; IPR024727; NAD_Glu_DH_N_ACT1.
DR PANTHER; PTHR43403; NAD-SPECIFIC GLUTAMATE DEHYDROGENASE; 1.
DR PANTHER; PTHR43403:SF1; NAD-SPECIFIC GLUTAMATE DEHYDROGENASE; 1.
DR Pfam; PF05088; Bac_GDH_CD; 1.
DR Pfam; PF21075; GDH_ACT1; 1.
DR Pfam; PF21076; GDH_ACT2; 1.
DR Pfam; PF21077; GDH_ACT3; 1.
DR Pfam; PF21074; GDH_C; 1.
DR Pfam; PF21073; GDH_HM1; 1.
DR Pfam; PF21078; GDH_HM3; 1.
DR PIRSF; PIRSF036761; GDH_Mll4104; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 40..163
FT /note="NAD-glutamate dehydrogenase N-terminal ACT1"
FT /evidence="ECO:0000259|Pfam:PF21075"
FT DOMAIN 393..481
FT /note="NAD-glutamate dehydrogenase ACT2"
FT /evidence="ECO:0000259|Pfam:PF21076"
FT DOMAIN 546..603
FT /note="NAD-glutamate dehydrogenase ACT3"
FT /evidence="ECO:0000259|Pfam:PF21077"
FT DOMAIN 709..1198
FT /note="NAD-glutamate dehydrogenase catalytic"
FT /evidence="ECO:0000259|Pfam:PF05088"
FT DOMAIN 1244..1573
FT /note="NAD-specific glutamate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21074"
SQ SEQUENCE 1582 AA; 181309 MW; 122B6656E4408FE5 CRC64;
MTPKTTSLNF SRLNCQIPNY KTKILELSKE RESSSIYIDF VQKFLNYIPI DYDFENRAKL
FQNFADEAFK FFKQRIARAR KIAITKAVIE NDPAINVLIL LDNKPHIVDF IICLLKNMNL
HTKFLLHPVI NCVRNSKGEL EKILENSVSD EKSESILHLT ILGNFDDKTT TFLTEAINER
LEKLEQSYSH LPQLRTKLQD LSKNIIDNYK LNFKEAKEFL NWLQNDNLVL LGTLDFEVKS
LKLSNEIGAE KIWQEVKDEI DDIIKCSANP LYQNQLIILG KINSASLIHS DNLIDYILVK
NFDSSGEYIS GSIIFGIYNS NMYYHSISNI PILRQKFNFV IEKAGFALSG YNADKLRILM
ESLPREALIQ IDQGDLYCMC LHMLSSMMSK KLKLFIQYDW SSSFLNIIIF LPRERLTAEI
HNMIDCYLAE KFGSKILSNY ITEVAGNFSY LFVTLEAQGE HKISFEAEII QQDLDRISTC
WSEDFYFKFS KKFGEYQTGI NLKLFDNVFS ADYRQKFSPE IALVDIEYLT EASKSQKCMF
NLVSVNETEF YLKIYSPKVK LALSNILPPI ENLGFKAIDE QTFAIKEALE IKESWIYNFI
LTSIVPVKDN ITELKINVEE ALDKMALGML ANDSLSKLIV LAGFNWKQVK LVKALTRYLH
QTGFSYGKGY VQLTLLKHPE YTKMLVNLFD IKFNPKHSDN NCDVIKDKLN NYLVTVEMSS
EDKVLRNMLG IVNAITRTNY YQPHKHIFSF KFDSSKVPDL PKPVPFAEAF VYSRNFEAVH
LRGGPVSRGG LRWSDRAEDY RLEVLGLMKA QMTKNSVIVP VGSKGGFYVH FTEEGLTRDE
YMEKVVECYK NFLRGLLDIT DNIIDGKVVH PKDVIIYDKE DPYLVVAADK GTASFSDYAN
SVAREYNYWL DDAFASGGSA GYDHKKMAIT SKGAWISVTN HFKTLGLDVQ KDPITVVGIG
DMSGDVFGNG MLRSETIKLV AAFNHKHIFI DPTPDPLSSF NERLRLFNLK GSNWSDYDSK
LISKGGKVFE RSSKLIKLSP EIKKLLDIND NELSPEELIK AILKAGVDLL WNGGIGTYIK
AKTENNLEIG DKANDNLRCN GEEIRAKVIA EGGNVGVSQR GRVEYAKKGG RINADFIDNS
AGVDCSDHEV NIKIALSSAI TSGKITLEER NKLLNDMTKQ VEELVLLDNY KQTEAITIMQ
LSPTLTVNIL SQFIDILEEE KVLERENEFL PSAEELNSRA MSGEVLTRPE LCILLSYSKR
SAYHELINST FSHDKYFDAY LIDYFPEMMQ KKFRNEILSH PLKHEIIKTV TINKIMNQLG
GPLISIVKRE IGAPLCDIIR SYTIICEIFD LDDIWETISK LPTNIDYNVK IDMFTEITKL
MRRGISWFIK NLKHPINISE TIEEFRVPAQ NLRKTVDTLL VGETKIRFEE KLNYYTTSGV
EESLAATIAT FDNLISVFDI IYVTKQTSGN NKEIAKAYFV ISDMFSLDWL RKACDRQLND
SFWRRLGIQS LKDDLYDKQR RLLIKIINKS KTTIDLDLWI DNNNLVRNLL DFIKEIKAQE
TIDLNIIILA NKKFEIFLQK LE
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