ID H8XQR1_FLAIG Unreviewed; 697 AA.
AC H8XQR1;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Probable phosphoglycerol transferase {ECO:0000313|EMBL:CCG53359.1};
DE EC=2.7.8.20 {ECO:0000313|EMBL:CCG53359.1};
GN OrderedLocusNames=KQS_07000 {ECO:0000313|EMBL:CCG53359.1};
OS Flavobacterium indicum (strain DSM 17447 / CIP 109464 / GPTSA100-9).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1094466 {ECO:0000313|EMBL:CCG53359.1, ECO:0000313|Proteomes:UP000007599};
RN [1] {ECO:0000313|EMBL:CCG53359.1, ECO:0000313|Proteomes:UP000007599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17447 / CIP 109464 / GPTSA100-9
RC {ECO:0000313|Proteomes:UP000007599};
RX PubMed=22582381; DOI=10.1128/JB.00420-12;
RA Barbier P., Houel A., Loux V., Poulain J., Bernardet J.F., Touchon M.,
RA Duchaud E.;
RT "Complete Genome Sequence of Flavobacterium indicum GPSTA100-9T, Isolated
RT from Warm Spring Water.";
RL J. Bacteriol. 194:3024-3025(2012).
RN [2] {ECO:0000313|Proteomes:UP000007599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17447 / CIP 109464 / GPTSA100-9
RC {ECO:0000313|Proteomes:UP000007599};
RA Barbier P., Houel A., Loux V., Poulain J., Bernardet J.-F., Touchon M.,
RA Duchaud E.;
RT "Complete genome sequence of Flavobacterium indicum GPTSA100-9T, isolated
RT from warm spring water.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HE774682; CCG53359.1; -; Genomic_DNA.
DR RefSeq; WP_014388484.1; NC_017025.1.
DR AlphaFoldDB; H8XQR1; -.
DR STRING; 1094466.KQS_07000; -.
DR KEGG; fin:KQS_07000; -.
DR PATRIC; fig|1094466.5.peg.1378; -.
DR eggNOG; COG1368; Bacteria.
DR HOGENOM; CLU_014653_1_0_10; -.
DR OrthoDB; 9777768at2; -.
DR Proteomes; UP000007599; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008960; F:phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity; IEA:UniProtKB-EC.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.30.1120.80; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012160; LtaS-like.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF005091; Mmb_sulf_HI1246; 2.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Manganese {ECO:0000256|PIRSR:PIRSR005091-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR005091-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000007599};
KW Transferase {ECO:0000313|EMBL:CCG53359.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 325..595
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT ACT_SITE 373
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-1"
FT BINDING 333
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 373
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 491
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-2"
FT BINDING 544
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 545
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
SQ SEQUENCE 697 AA; 80015 MW; 18E2BC2DF2AFBB59 CRC64;
MKNLLKHHVV YKNIALFYLI VSLLTRVILL IHPITQSHFS FVDYLKIFSF GILNDLFVFV
LIGFILWLYL IFISDSKFKK PYGYLILGIF VCTLLYIASG KSILSEYGGV LPEIGLAFVG
LKTILFALLL FFEKNRKKIR FVLFSFTIFL FVLLIIQNAV SEFFFWNEFG VRYNFIAVDY
LVYTNTVIGN IMESYPVVPL FSIIGIVSVL STYFIIQKSK KYLDEIPNIK AKISIVLGQL
ALIALALFTI PNLAKKEDSS NVFTNELQSN GLYKFYLAFM NSELDFMKFY DTLPENELAN
FENTTHIKLN QNTVHIQPTE KEIHKNVVLI TIESMSAEFM KHYGNTENIT PFLDELADKS
LFFTNLYATG NRTVRGLEAV TLCLPPTPGE SVVKRKDNKN KFSTGCIFKS KGYQIKYLYG
GDAFFDNMQD FYKGNGYDIV DKSSLKPNEI SFSNIWGVCD EDMAKKAIKV MNAEYQTGKP
FFNHWMTVSN HRPFTYPDGK IDIPANSKSR NGGVKYTDYA LKQFFALAEK QPWFKNTVFV
IVADHCASSS GKVELPLEKY RIPAMIYAPG FIKSQKCNTL MSQIDLMPTA LGLLNFKYRS
KFFGENIFNP TYTPRAFIAT YQDLGYIKDN YLTIISPVKR VKQFVLKPKS NSNYEIHFDE
LANTKINKKL EFETIAFYEE AALLLKNHKY QAIHGTK
//
