ID H8XS08_FLAIG Unreviewed; 809 AA.
AC H8XS08;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Putative efflux transporter, RND superfamily {ECO:0000313|EMBL:CCG54592.1};
GN OrderedLocusNames=KQS_13475 {ECO:0000313|EMBL:CCG54592.1};
OS Flavobacterium indicum (strain DSM 17447 / CIP 109464 / GPTSA100-9).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1094466 {ECO:0000313|EMBL:CCG54592.1, ECO:0000313|Proteomes:UP000007599};
RN [1] {ECO:0000313|EMBL:CCG54592.1, ECO:0000313|Proteomes:UP000007599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17447 / CIP 109464 / GPTSA100-9
RC {ECO:0000313|Proteomes:UP000007599};
RX PubMed=22582381; DOI=10.1128/JB.00420-12;
RA Barbier P., Houel A., Loux V., Poulain J., Bernardet J.F., Touchon M.,
RA Duchaud E.;
RT "Complete Genome Sequence of Flavobacterium indicum GPSTA100-9T, Isolated
RT from Warm Spring Water.";
RL J. Bacteriol. 194:3024-3025(2012).
RN [2] {ECO:0000313|Proteomes:UP000007599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17447 / CIP 109464 / GPTSA100-9
RC {ECO:0000313|Proteomes:UP000007599};
RA Barbier P., Houel A., Loux V., Poulain J., Bernardet J.-F., Touchon M.,
RA Duchaud E.;
RT "Complete genome sequence of Flavobacterium indicum GPTSA100-9T, isolated
RT from warm spring water.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HE774682; CCG54592.1; -; Genomic_DNA.
DR RefSeq; WP_014389710.1; NC_017025.1.
DR AlphaFoldDB; H8XS08; -.
DR STRING; 1094466.KQS_13475; -.
DR KEGG; fin:KQS_13475; -.
DR PATRIC; fig|1094466.5.peg.2640; -.
DR eggNOG; COG1033; Bacteria.
DR HOGENOM; CLU_008861_1_0_10; -.
DR OrthoDB; 9805018at2; -.
DR Proteomes; UP000007599; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007599};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 621..640
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 647..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 722..740
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 746..774
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 257..382
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 624..773
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 809 AA; 92741 MW; C88AF0C48255D2B8 CRC64;
MKKWLSTSFW ILISRFLLRN RLLVIVMIAA FTVFMGMQWK YIRFTQTEAN LLPDDHKDNI
AYTNFLKKFG EEANLIVFAV KSDEVFKPEN FKAWSEMMQN IQQNKKEVDF VISFKELKQL
VKNDSTQAFE LKPFIDENKL TEVNYLQDKR KELIHNLPFY ESLLFNKKSG VVRSVIYLNK
NIVNTKIRKD FVLEKLIPEI NKFKEKTKVD IRVSGMPYIR TLNATAIISE IGLFIGATLL
VTSLIFYFFF RSFRTTLMAI FVVIIGVMWS FGLLGLLRYE ITVLTALVPS LIVIIGIPNC
IFLTNKYHQE ARAHGNRAKA LQRVLTKVGT ATFITNVTTA VGFATFIITN NQLLSEFGVV
TSLNIMALFV LSLFVIPIFF SFLPIPKDKH LEHLERSYLV GFRDWIINQV KYHNVRVYAV
ALTLLIAGII GVYKMKISGS VLEDMPKNQP FFEDIRFFEK EFKGVLPVEI MIDTKRKKGV
MKMSTLKKID ELQREIEEIP QLSKPVSIVN LVKYAKQAYY NGNPEYYDLP NSQEQAFILP
YLKNSAKDGK ENPLKSYVDK TGQYARISTF MKEVGTDEME EVEKKLNEKI KELFPEDRYT
VAITGKALLF QKGTSYLLDN LIESLIFAVA LTAGLIFFLF RSVKMIFVAL IPNLLPLLCT
AGLMGYLEIP IKPSTILVFG IAFGLSVDDT IRFLAQYRQE LKINNWKIKK SIFKTLEEEG
PSMFYTSIVL LCGFFVFTLS DFGGTVALGG LVSITLLFGM LTNLILLPSL VLSLNRTLAN
QQEMKEPTLD IVVSDDEIEE EIEQKNKQD
//
