ID   H8Y200_9NEOB            Unreviewed;        71 AA.
AC   H8Y200;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   16-MAY-2012, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Antimicrobial peptide {ECO:0000313|EMBL:AEZ52992.1};
OS   Odorrana tiannanensis (Dawei frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Odorrana.
OX   NCBI_TaxID=448113 {ECO:0000313|EMBL:AEZ52992.1};
RN   [1] {ECO:0000313|EMBL:AEZ52992.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=21963433; DOI=10.1016/j.biochi.2011.09.017;
RA   He W., Feng F., Huang Y., Guo H., Zhang S., Li Z., Liu J., Wang Y., Yu H.;
RT   "Host defense peptides in skin secretions of Odorrana tiannanensis: Proof
RT   for other survival strategy of the frog than merely anti-microbial.";
RL   Biochimie 94:649-655(2012).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC       Brevinin subfamily. {ECO:0000256|ARBA:ARBA00008230}.
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DR   EMBL; JF329985; AEZ52992.1; -; mRNA.
DR   AlphaFoldDB; H8Y200; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:UniProt.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:UniProt.
DR   InterPro; IPR012520; Antimicrobial_frog_1.
DR   InterPro; IPR004275; Frog_antimicrobial_propeptide.
DR   Pfam; PF08018; Antimicrobial_1; 1.
DR   Pfam; PF03032; FSAP_sig_propep; 1.
PE   2: Evidence at transcript level;
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..71
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003617168"
FT   DOMAIN          3..46
FT                   /note="Frog antimicrobial peptide propeptide"
FT                   /evidence="ECO:0000259|Pfam:PF03032"
FT   DOMAIN          48..71
FT                   /note="Frog antimicrobial peptide brevinin-1 type"
FT                   /evidence="ECO:0000259|Pfam:PF08018"
SQ   SEQUENCE   71 AA;  8212 MW;  7E2606061643457C CRC64;
     MLTLKKSLLL LFFLGTINLS LSEQERDADE EERRDDSEER DIEVEKRFLP LIASVAANLV
     PKIFCKITKK C
//